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FIGURE: 1 / 4
Sequence of this protein is as follows: MPVQLSEHPE WNESMHSLRI SVGGLPVLAS MTKAADPRFR PRWKVILTFF VGAAILWLLC SHRPAPGRPP THNAHNWRLG QAPANWYNDT YPLSPPQRTP AGIRYRIAVI ADLDTESRAQ EENTWFSYLK KGYLTLSDSG DKVAVEWDKD HGVLESHLAE KGRGMELSDL IVFNGKLYSV DDRTGVVYQI EGSKAVPWVI LSDGDGTVEK GFKAEWLAVK DERLYVGGLG KEWTTTTGDV VNENPEWVKV VGYKGSVDHE NWVSNYNALR AAAGIQPPGY LIHESACWSD TLQRWFFLPR RASQERYSEK DDERKGANLL LSASPDFGDI AVSHVGAVVP THGFSSFKFI PNTDDQIIVA LKSEEDSGRV ASYIMAFTLD GRFLLPETKI GSVKYEGIEF I
This protein encoded by this gene belongs to the apyrase family. It functions as a calcium-dependent nucleotidase with a preference for UDP. Mutations in this gene are associated with Desbuquois dysplasia with hand anomalies.
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Protein Aliases: apyrase 1, homolog (C. lectularius); Apyrase homolog; Ca2+-dependent endoplasmic reticulum nucleoside diphosphatase; EC 3.6.1.6; micromelic dwarfism with vertebral and metaphyseal abnormalities and advanced carpotarsal ossification; Putative MAPK-activating protein PM09; Putative NF-kappa-B-activating protein 107; SCAN-1; soluble Ca-activated nucleotidase, isozyme 1; Soluble calcium-activated nucleotidase 1; soluble calcium-activated nucleotidase SCAN-1
Gene Aliases: 5830420C20Rik; Apy1h; CANT1; D11Bwg0554e; DBQD; DBQD1; Entpd8; SCAN-1; SCAN1; SHAPY
UniProt ID: (Human) Q8WVQ1, (Mouse) Q8VCF1
Entrez Gene ID: (Human) 124583, (Mouse) 76025
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