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CAR Antibody (PA5-95942) in WB
Western blot analysis of CAR in extracts of various cell lines. Samples were incubated with CAR Polyclonal antibody (Product # PA5-95942) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3s.
产品信息
PA5-95942
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 20-237 of human CAR/CXADR (NP_0013291)
偶联物
形式
Liquid
浓度
0.34 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2807744
产品详细信息
Immunogen sequence: LSITTPEEMI EKAKGETAYL PCKFTLSPED QGPLDIEWLI SPADNQKVDQ VIILYSGDKI YDDYYPDLKG RVHFTSNDLK SGDASINVTN LQLSDIGTYQ CKVKKAPGVA NKKIHLVVLV KPSGARCYVD GSEEIGSDFK IKCEPKEGSL PLQYEWQKLS DSQKMPTSWL AEMTSSVISV KNASSEYSGT YSCTVRNRVG SDQCLLRLNV VPPSNKAG; Positive Samples: HeLa, OVCAR3, SW480, HepG2, PC-3, Mouse liver, Mouse heart; Cellular Location: Basolateral cell membrane, Cell junction, Cell membrane, Single-pass membrane protein, Single-pass type I membrane protein, Single-pass type I membrane protein, adherens junction, tight junction
靶标信息
The protein encoded by this gene is a type I membrane receptor for group B coxsackieviruses and subgroup C adenoviruses. Pseudogenes of this gene are found on chromosomes 15, 18, and 21.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 46 kD coxsackievirus and adenovirus receptor (CAR) protein; CAR; Coxsackievirus and adenovirus receptor; Coxsackievirus and adenovirus receptor homolog; Coxsackievirus B-adenovirus receptor; CVB3-binding protein; HCVADR; rCAR
基因别名: 2610206D03Rik; AU016810; AW553441; CAR; Car1; CAR4/6; CXADR; HCAR; MCAR; MCVADR
UniProt ID: (Human) P78310, (Mouse) P97792, (Rat) Q9R066
Entrez Gene ID: (Human) 1525, (Mouse) 13052, (Rat) 89843
mitochondrion organization
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
heart development
germ cell migration
epithelial structure maintenance
neutrophil chemotaxis
actin cytoskeleton reorganization
cell-cell junction organization
gamma-delta T cell activation
viral entry into host cell
cardiac muscle fiber development
regulation of immune response
leukocyte migration
transepithelial transport
AV node cell to bundle of His cell communication
cell adhesion
single organismal cell-cell adhesion
homotypic cell-cell adhesion
defense response to virus
negative regulation of cardiac muscle cell proliferation
positive regulation of epithelial cell proliferation involved in wound healing
AV node cell-bundle of His cell adhesion involved in cell communication
regulation of AV node cell action potential
