Invitrogen

CAT1 Polyclonal Antibody

CAT1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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CAT1 Antibody (PA5-82673) in IHC (P)

Immunohistochemical analysis of CAT1 in human testis using CAT1 Polyclonal Antibody (Product # PA5-82673) shows moderate to strong cytoplasmic positivity in cells in seminiferous ducts.

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CAT1 Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of CAT1 demonstrates antibody specificity. Immunohistochemical analysis of CAT1 using anti-CAT1 Polyclonal Antibody (Product #PA5-82673), shows significant staining of CAT1 in testis and shows minimal or weak staining in lymph node tissues. The relative expression levels of CAT1 within each tissue is shown using RNA-Seq. {RE}

产品信息

PA5-82673

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.04-0.4 µg/mL

免疫组化（石蜡） (IHC (P))

1:200-1:500

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human CRAT. Recombinant protein control fragment (Product #RP-92889).

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2789829

产品详细信息

Immunogen sequence: RWFDKTLQFI VAEDGSCGLV YEHAAAEGPP IVTLLDYVIE YTKKPELVRS PMVPLPMPKK LRFNITPEIK SDIEKAKQNL SIMIQDLDIT VMVFHHFGKD F

靶标信息

Carnitine acetyltransferase (CRAT) is a key enzyme in the metabolic pathway in mitochondria, peroxisomes and endoplasmic reticulum. CRAT catalyzes the reversible transfer of acyl groups from an acyl-CoA thioester to carnitine and regulates the ratio of acylCoA/CoA in the subcellular compartments. Different subcellular localizations of the CRAT mRNAs are thought to result from alternative splicing of the CRAT gene suggested by the divergent sequences in the 5' region of peroxisomal and mitochondrial CRAT cDNAs and the location of an intron where the sequences diverge. The alternatively splicing of this gene results in three distinct isoforms, one of which contains an N-terminial mitochondrial transit peptide, and has been shown to be located in mitochondria.

仅用于科研。不用于诊断过程。未经明确授权不得转售。