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产品信息
MA5-17273
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
GT519
抗原
Recombinant protein fragment contains a sequence corresponding to a region within amino acids 39 and 251 of CBS
偶联物
形式
Liquid
浓度
0.97 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2538739
产品详细信息
Recommended positive controls: HeLa, 293T, Raji, K562, mouse liver, rat liver.
Predicted reactivity: Mouse (94%), Rat (94%), Xenopus laevis (93%), Rabbit (95%), Bovine (94%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Only known pyridoxal phosphate-dependent enzyme that contains heme. Important regulator of hydrogen sulfide, especially in the brain, utilizing cysteine instead of serine to catalyze the formation of hydrogen sulfide. Hydrogen sulfide is a gastratransmitter with signaling and cytoprotective effects such as acting as a neuromodulator in the brain to protect neurons against hypoxic injury.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Beta-thionase; Cystathionine beta-synthase; cystathionine-beta-synthase; Hemoprotein H-450; methylcysteine synthase; Serine sulfhydrase
基因别名: AI047524; AI303044; CBS; HIP4
UniProt ID: (Human) P35520, (Rat) P32232, (Mouse) Q91WT9
Entrez Gene ID: (Human) 875, (Rat) 24250, (Mouse) 12411
cystathionine beta-synthase activity
cysteine synthase activity
protein binding
oxygen binding
enzyme binding
heme binding
pyridoxal phosphate binding
ubiquitin protein ligase binding
identical protein binding
protein homodimerization activity
metal ion binding
nitrite reductase (NO-forming) activity
carbon monoxide binding
nitric oxide binding
modified amino acid binding
S-adenosyl-L-methionine binding
lyase activity
lyase
metabolite interconversion enzyme
cysteine biosynthetic process from serine
L-serine metabolic process
L-serine catabolic process
cellular amino acid biosynthetic process
cysteine biosynthetic process via cystathionine
cysteine biosynthetic process
transsulfuration
L-cysteine catabolic process
DNA protection
homocysteine catabolic process
homocysteine metabolic process
oxidation-reduction process
hydrogen sulfide biosynthetic process
endochondral ossification
blood vessel remodeling
superoxide metabolic process
cerebellum morphogenesis
regulation of cGMP metabolic process
response to nutrient levels
negative regulation of apoptotic process
regulation of JUN kinase activity
regulation of blood vessel size
response to folic acid
maternal process involved in female pregnancy
cartilage development involved in endochondral bone morphogenesis
cellular response to hypoxia
