Invitrogen

CCDC23 Polyclonal Antibody

CCDC23 Antibody in Immunohistochemistry (IHC)

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CCDC23 Antibody (PA5-52569) in IHC

Immunohistochemical staining of CCDC23 in human placenta using CCDC23 Polyclonal Antibody (Product # PA5-52569) shows weak to moderate nuclear positivity in a subset of trophoblastic cells.

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产品信息

PA5-52569

应用

建议稀释比

已发表文章

免疫印迹 (WB)

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免疫组化（石蜡） (IHC (P))

1:20-1:50

产品规格

种属反应

Human

已发表种属

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human CCDC23. Recombinant protein control fragment (Product #RP-89736).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2639441

产品详细信息

Immunogen sequence: DPPARKEKTK VKESVSRVEK AKQKSAQQEL KQRQRAEIYA LNRVMTELEQ QQFDEFCKQM QPPGE

Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Tubulin Carboxypeptidase Activity Promotes Focal Gelatin Degradation in Breast Tumor Cells and Induces Apoptosis in Breast Epithelial Cells That Is Overcome by Oncogenic Signaling.

Cancers

Mathias TJ,Ju JA,Lee RM,Thompson KN,Mull ML,Annis DA,Chang KT,Ory EC,Stemberger MB,Hotta T,Ohi R,Vitolo MI,Moutin MJ,Martin SS

PA5-52569 was used in Western Blot to reveal the immortalized breast epithelial cell line MCF10A undergoes apoptosis following transfection with TCP constructs, but the addition of oncogenic KRas or Bcl-2/Bcl-xL overexpression prevents subsequent apoptotic induction in the MCF10A background.

Mon Mar 28 00:00:00 UTC 2022

生物信息学

蛋白别名: Coiled coil domain-containing protein 23; coiled-coil domain containing 23; coiled-coil domain-containing protein 23; Small vasohibin-binding protein

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基因别名: CCDC23; SVBP

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UniProt ID: (Human) Q8N300

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Entrez Gene ID: (Human) 374969

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参与通路

protein secretion negative regulation of endothelial cell migration negative regulation of protein ubiquitination