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产品信息
PA5-33389
产品规格
种属反应
Human
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 18 amino acid peptide from 3rd cytoplasmic domain of human CCKBR.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2550770
产品详细信息
Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon (100%) Monkey (83%).
靶标信息
CCKBR is a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors. CCKBR has been reported in brain, colon, pancreas, stomach, thyroid, and various cancers.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: CCK-B receptor; CCK-BR; CCK2 receptor; CCK2-R; CCKB; Cckb receptor; CCKB-R; Cholecystokinin-2 receptor; Cholecystokinin-B; gastrin receptor; Gastrin/cholecystokinin type B receptor; HGNC:1571
基因别名: CCK-B; CCK2R; CCKBR; CCKRB; GASR
UniProt ID: (Human) P32239
Entrez Gene ID: (Human) 887
gastric acid secretion
cell surface receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
digestion
sensory perception
feeding behavior
cell proliferation
positive regulation of cell proliferation
cholecystokinin signaling pathway
regulation of phosphatidylinositol 3-kinase activity
digestive tract development
gland development
