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CCL1 Antibody (PA5-21941) in IHC (P)
CCL1 Polyclonal Antibody detects CCL1 protein at cytosol on human breast cancer by immunohistochemical analysis. Sample: Paraffin-embedded breast cancer. CCL1 Polyclonal Antibody (Product # PA5-21941) dilution: 1:250. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
产品信息
PA5-21941
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to a region within amino acids 32 and 96 of I-309 (Uniprot ID#P22362)
偶联物
形式
Liquid
浓度
0.55 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_11157646
产品详细信息
Recommended positive controls: Molt-4.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine receptor CCR8.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C-C motif chemokine 1; CCL 1; chemokine (C-C motif) ligand 1; inflammatory cytokine I-309; small inducible cytokine A1 (I-309, homologous to mouse Tca-3); Small-inducible cytokine A1; T lymphocyte-secreted protein I-309
基因别名: CCL1; I-309; P500; SCYA1; SISe; TCA3
UniProt ID: (Human) P22362
Entrez Gene ID: (Human) 6346
monocyte chemotaxis
cellular calcium ion homeostasis
chemotaxis
inflammatory response
signal transduction
G-protein coupled receptor signaling pathway
viral process
neutrophil chemotaxis
positive regulation of GTPase activity
lymphocyte chemotaxis
positive regulation of inflammatory response
response to glucocorticoid
chemokine-mediated signaling pathway
positive regulation of ERK1 and ERK2 cascade
cellular response to interferon-gamma
cellular response to interleukin-1
cellular response to tumor necrosis factor
