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CCL1 Antibody (PA5-47952) in Neu
Neutralization of CCL1 in BaF3 mouse pro‚B cell line transfected with mouse CCR8. Samples were incubated in CCL1 polyclonal antibody (Product # PA5-47952). Recombinant Mouse CCL1/TCA‚3 chemoattracts the BaF3 mouse pro‚B cell line transfected with mouse CCR8 in a dose-dependent manner (orange line). The amount of cells that migrated through to the lower chemotaxis chamber was measured by Resazurin. Chemotaxis elicited by Recombinant Mouse CCL1/TCA‚3 (0.01 µg/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Mouse CCL... View More
产品信息
PA5-47952
产品规格
种属反应
Mouse
已发表种属
Mouse
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Sf 21-derived recombinant mouse CCL1/I-309/TCA-3 Lys24-Cys92
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2609540
产品详细信息
In Western blots, approximately 10% cross-reactivity with recombinant humanI-309 is observed and 2% cross-reactivity with recombinant mouse MCP-5 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
靶标信息
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine receptor CCR8.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: C-C motif chemokine 1; CCL 1; CCR8 ligand; P500; SIS-epsilon; small inducible cytokine A1; Small-inducible cytokine A1; T-cell activation protein 3; TCA-3; TCA3
基因别名: BF534335; Ccl1; I-309; Scya1; Tca-3; Tca3
UniProt ID: (Mouse) P10146
Entrez Gene ID: (Mouse) 20290
