Invitrogen

CD100 Recombinant Rabbit Monoclonal Antibody (010), FITC

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CD100 Antibody (MA5-46846) in Flow

Flow cytometry analysis of CD100 (SEMA4D) in mouse splenocytes using CD100, FITC Recombinant Monoclonal (Product # MA5-46846).

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产品信息

MA5-46846

应用

建议稀释比

已发表文章

流式细胞分析 (Flow)

10 µL/test

产品规格

种属反应

Mouse

宿主/亚型

Rabbit / IgG

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

010

抗原

Recombinant protein encoding Mouse CD100 (Met1-Arg733).

查看免疫原

偶联物

FITC FITC FITC

激发/发射光谱

498/517 nm 查看光谱

形式

Liquid

浓度

100 µg/mL

纯化类型

Protein A

保存液

PBS with 0.5% BSA

内含物

0.09% sodium azide

保存条件

4° C, store in dark, DO NOT FREEZE!

运输条件

Ambient (domestic); Wet ice (international)

AB_2937918

产品详细信息

Preparation: This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD100 (SEMA4D) (Met1-Arg733) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.

Storage: This antibody can be stored at 2C-8C for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

靶标信息

Semaphorins are neuronal chemorepellants that direct pioneering neurons during nervous system development. CD100 (also known as semaphorin 4d), a 150 kDa homodimer, is a novel semaphorin that induces B cells to aggregate and improves their viability in vitro. CD100 modifies CD40-CD40L B cell signaling by augmenting B cell aggregation and survival and down regulating CD23 expression. CD72 is a lymphocyte receptor for the class IV semaphorin CD100, which is involved in regulating B cell signaling. CD100 is expressed on resting and PHA stimulated T cells. The protein is weakly expressed on NK cells, EBV transformed B cells, monocytes and tumor/peripheral blood T cell lines, and at higher density on activated T cells and B cells.

仅用于科研。不用于诊断过程。未经明确授权不得转售。