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产品信息
MA5-23527
产品规格
种属反应
Mouse
宿主/亚型
Rat
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
300506
抗原
Mouse myeloma cell line NS0-derived recombinant mouse Syndecan-1/CD138 isoform 1 Gln18-Glu252
偶联物
激发/发射光谱
565/576 nm
查看光谱
形式
Liquid
纯化类型
Protein A/G
保存液
Buffered saline solution with BSA
内含物
0.09% sodium azide
保存条件
4° C, store in dark, DO NOT FREEZE!
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2609280
产品详细信息
In direct ELISAs, no cross-reactivity with recombinant human Syndecan-1, recombinant mouse (rm) Syndecan-3 or rmSyndecan-4 is observed.
靶标信息
CD138 (syndecan 1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes. CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury. It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells. Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics. Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
How to use the Panel Builder
Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.
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生物信息学
蛋白别名: CD antigen 138; CD138; sCD138; soluble CD138; SYND1; Syndecan-1; Syndecan1; synstatin
基因别名: AA408134; AA409076; CD138; Sdc1; Sstn; syn-1; Synd; Synd-1; Synd1
UniProt ID: (Mouse) P18828
Entrez Gene ID: (Mouse) 20969
