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MA5-17931 targets CD147/BSG in FACS applications and shows reactivity with Mouse samples.
The MA5-17931 immunogen is recombinant md0-2rCD4d3+4.
CD147 (basigin, neurothelin, OX-47, 5A11, CE9, M6, EMMPRIN, extracellular matrix metalloproteinase inducer, TCSF, tumour cell-derived collagenase-stimulatory factor) is a 50-60 kDa glycoprotein with multiple glycosylated forms. CD147 is a plasma membrane protein that is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is also a member of the immunoglobulin superfamily. The highest level of CD147 expression is on metabolically active cells, such as lymphoblasts, inflammatory cells, brown adipocytes and malignant tumor cells. CD147 has multiple functions, including facilitating of cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulation of integrin functions, it plays roles in cell development and activation, fetal development or retinal function.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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蛋白别名: 5A11/Basigin; Basic immunoglobulin superfamily; Basigin; CD147; gp 42; HT7 antigen; Membrane glycoprotein gp42; neurothelin
基因别名: AI115436; AI325119; Bsg; CD147; EMMPRIN; HT-7
UniProt ID: (Mouse) P18572
Entrez Gene ID: (Mouse) 12215