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产品信息
MA5-29852
产品规格
种属反应
Rhesus monkey
宿主/亚型
Mouse
分类
Monoclonal
类型
Antibody
克隆号
05
抗原
Recombinant Rhesus CD16/Fc gamma RIII Protein
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2785669
产品详细信息
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Rhesus CD16/Fc gamma RIII.
靶标信息
CD16 is a 50-65 kDa cell surface molecule that exists in two forms - a transmembranous form expressed by natural killer (NK) cells, and some T cells and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC (antibody dependent cell mediated cytotoxicity) by NK cells. IN comparison, CD32 is a 40 kD glycoprotein that acts as a low affinity receptor for IgG (also known as Fc gamma RII), and mediates several functions including endocytosis, activation of secretion, cytotoxicity and immunomodulation. CD32 is expressed by B cells, monocytes, granulocytes and platelets. Further, CD32 is involved in the phagocytosis of immune complexes, the regulation of antibody production by B-cells, and variations of the CD32 gene may increase vulnerability to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms of CD32 have been found.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD16A; CD16B; CD32 receptor 2; CDw32; Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc gamma receptor RII; Fc gamma RIIIa; Fc-gamma RII-b; Fc-gamma RII-c; Fc-gamma RIII; Fc-gamma RIII-alpha; Fc-gamma-RIIc; FCG2; FCGR2C; FCGR3A; FCGR3B; FCGRIII; FCR-10; FcRII-b; FcRII-c; FCRIIIA; FGFR2B; IgG Fc receptor III; IgG Fc receptor III-A; Low affinity immunoglobulin gamma Fc region receptor III-A; RP11-5K23.1
基因别名: CD16; CD32B; FCGR3; FCGR3A; FcRIII
UniProt ID: (Rhesus monkey) A3RFZ7
Entrez Gene ID: (Rhesus monkey) 720009, (Rhesus monkey) 720006
