Invitrogen

CD200 Polyclonal Antibody

CD200 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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CD200 Antibody (PA5-145283) in IHC (P)

Immunohistochemistry (Paraffin) analysis of CD200 in Human Prostate Tissue. Samples were incubated in CD200 polyclonal antibody (Product # PA5-145283) using a dilution of 10 µg/mL followed by HRP-Linked Caprine Anti-Rabbit IgG at a dilution of 2 µg/mL and DAB staining.

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产品信息

PA5-145283

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.5-2 µg/mL

免疫组化（石蜡） (IHC (P))

5-20 µg/mL

产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant Human CD200 protein, Gln31-Gly232 (Accession #P41217)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.05% Proclin 300

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_3093577

靶标信息

CD200 is a type-1 membrane glycoprotein that contains two immunoglobulin domains, and belongs to the immunoglobulin superfamily. CD200 is a broadly distributed cell surface glycoprotein that interacts with a receptor on myeloid cells (CD200R) and is implicated in locally preventing macrophage activation. Distant, but recognizable, homologues of CD200 have been identified in many herpesviruses and poxviruses. Studies of the related genes in mouse and rat suggest that CD200 may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms of CD200 have been found. Diseases associated with CD200 dysfunction include Mantle Cell Lymphoma and Primary Hypertrophic Osteoarthropathy.

仅用于科研。不用于诊断过程。未经明确授权不得转售。