Invitrogen

CD226 Polyclonal Antibody

CD226 Antibody in Immunocytochemistry (ICC/IF)

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CD226 Antibody (PA5-31111) in ICC/IF

Immunofluorescence analysis of CD226 was performed using 70% confluent log phase Jurkat cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with CD226 Polyclonal Antibody (Product # PA5-31111) at 5 µg/mL in 0.1% BSA, incubated at 4 degree Celsius overnight and then labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034) at... View More

CD226 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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CD226 Antibody — Antibody specificity was demonstrated by detection of differential basal expression of the target across cell models owing to their inherent genetic constitution. Expression of CD226 was observed specifically in Platelets and PC-12 using Anti-CD226 Polyclonal Antibody (Product # PA5-31111) in Western Blot. {RE}

产品信息

PA5-31111

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:3,000

免疫组化（石蜡） (IHC (P))

1:100-1:1,000

免疫细胞化学 (ICC/IF)

5 µg/ml

产品规格

种属反应

Human, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fragment corresponding to a region within amino acids 1 and 274 of Human CD226

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7, with 1% BSA, 20% glycerol

内含物

0.01% thimerosal

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2548585

产品详细信息

Recommended positive controls: 293T, A431, Jurkat, Raji.

Predicted reactivity: Rhesus Monkey (92%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

靶标信息

DNAM 1 is a receptor expressed by peripheral blood T lymphocytes that is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T lymphocytes. DNAM 1 is broadly expressed on T cells, NK cells, platelets, monocytes and a subset of B cells. DNAM-1 is also expressed by a subset of CD3 positive thymocytes.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: adhesion glycoprotein; CD226; CD226 antigen; DNAM 1; DNAM-1; DNAX accessory molecule 1; DNAX accessory molecule-1; platelet and T cell activation antigen 1; T lineage-specific activation antigen 1 antigen

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基因别名: CD226; DNAM-1; DNAM1; PTA1; TLiSA1

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UniProt ID: (Human) Q15762

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Entrez Gene ID: (Human) 10666, (Rat) 307199

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功能

receptor activity integrin binding protein binding protein kinase binding protein homodimerization activity cell adhesion molecule binding molecular_function

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