Invitrogen

CD2AP Polyclonal Antibody

CD2AP Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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CD2AP Antibody (PA5-117848) in IHC (P)

Immunohistochemical staining of human CD2AP in human placenta with CD2AP Polyclonal Antibody (Product # PA5-117848, 1:100 dilution, formalin-fixed paraffin embedded sections).

CD2AP Antibody in Immunoprecipitation (IP)

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产品信息

PA5-117848

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:2,000-1:10,000

免疫组化（石蜡） (IHC (P))

1:50-1:200

免疫沉淀 (IP)

1-5 µL/mg of lysate

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

E. coli-derived Human CD2AP fragment

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

纯化类型

Antigen affinity chromatography, Protein A

保存液

PBS, pH 7

内含物

0.03% ProClin 300

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

AB_2902456

靶标信息

This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.

仅用于科研。不用于诊断过程。未经明确授权不得转售。