Invitrogen

CD31 Monoclonal Antibody (390), FITC

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CD31 Antibody (RM5201) in Flow

iScience 2023 - Pref-1 inhibits MIF release from both adipose Pref-1 cells and adipocytes (A) Cells with CD34 , CD31 , or CD45 in Pref-1 cells isolated from WAT in 20-week-WT mice by flow cytometry. (B) The percentages of CD34 , CD31 , or CD45 cells in Pref-1 cells following 8-week-NC or PD diet feeding. (C and D) M1 macrophages (CD45 F4/80 CD11b CD11c ) and M2 macrophages (CD45 F4/80 CD11b CD206 ) were ident... View More

CD31 Antibody in Immunohistochemistry (IHC)

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产品信息

RM5201

应用

建议稀释比

已发表文章

免疫组化 (IHC)

查看3篇已发表文章 3篇已发表文章

免疫组化（冰冻） (IHC (F))

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免疫细胞化学 (ICC/IF)

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流式细胞分析 (Flow)

Assay-dependent

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其他PubMed (Misc)

查看1篇已发表文章 1篇已发表文章

产品规格

种属反应

Mouse

已发表种属

Mouse

宿主/亚型

Rat / IgG2a, kappa

分类

Monoclonal

类型

Antibody

克隆号

390

抗原

Mouse 32D leukocyte cell line.

查看免疫原

偶联物

FITC FITC FITC

激发/发射光谱

498/517 nm 查看光谱

形式

Liquid

纯化类型

purified

保存液

PBS

内含物

0.1% sodium azide

保存条件

4° C, store in dark

运输条件

Ambient (domestic); Wet ice (international)

AB_10373983

靶标信息

CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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Product References

A pref-1-controlled non-inflammatory mechanism of insulin resistance.

iScience

Huang Y,Cui D,Chen L,Tong H,Wu H,Muller GK,Qi Y,Wang S,Xu J,Gao X,Fifield KE,Wang L,Xia Z,Vanderluit JL,Liu S,Leng L,Sun G,McGuire J,Young LH,Bucala R,Qi D

Published figure using CD31 monoclonal antibody (Product # RM5201) in Flow Cytometry

Fri Jun 16 00:00:00 UTC 2023

Myo1d promotes alpha-synuclein transfer from brain microvascular endothelial cells to pericytes through tunneling nanotubes.

iScience

Duan Q,Zhang Q,Nie K,Huang R,Yang J,He P,Tie Z,Huang H,Ma G,Zhang Y,Gao Y,Wang L

RM5201 was used in Immunocytochemistry to find that α-syn PFF spread from BMVECs to pericytes with the highest transmission efficiency.

Fri Aug 18 00:00:00 UTC 2023

Endothelial IK and SK channel activation decreases pulmonary arterial pressure and vascular remodeling in pulmonary hypertension.

Pulmonary circulation

Daneva Z,Chen YL,Ta HQ,Manchikalapudi V,Bazaz A,Laubach VE,Sonkusare SK

RM5201 was used in Immunocytochemistry to demonstrate proof of principle that IK/SK channel activation can be used as a strategy for lowering PAP in PH.

Sun Jan 01 00:00:00 UTC 2023

Vegfr3-tdTomato, a reporter mouse for microscopic visualization of lymphatic vessel by multiple modalities.

PloS one

Redder E,Kirschnick N,Bobe S,Hägerling R,Hansmeier NR,Kiefer F

Published figure using CD31 monoclonal antibody (Product # RM5201) in Flow Cytometry

Fri Nov 12 00:00:00 UTC 2021

Vegfr3-tdTomato, a reporter mouse for microscopic visualization of lymphatic vessel by multiple modalities.

PloS one

Redder E,Kirschnick N,Bobe S,Hägerling R,Hansmeier NR,Kiefer F

Published figure using CD31 monoclonal antibody (Product # RM5201) in Flow Cytometry

Fri Nov 12 00:00:00 UTC 2021

Pulmonary pericytes regulate lung morphogenesis.

Nature communications

Kato K,Diéguez-Hurtado R,Park DY,Hong SP,Kato-Azuma S,Adams S,Stehling M,Trappmann B,Wrana JL,Koh GY,Adams RH

Published figure using CD31 monoclonal antibody (Product # RM5201) in Flow Cytometry

Fri Jun 22 00:00:00 UTC 2018

PPARγ Controls Ectopic Adipogenesis and Cross-Talks with Myogenesis During Skeletal Muscle Regeneration.

International journal of molecular sciences

Dammone G,Karaz S,Lukjanenko L,Winkler C,Sizzano F,Jacot G,Migliavacca E,Palini A,Desvergne B,Gilardi F,Feige JN

RM5201 was used in Flow cytometry/Cell sorting to study muscle regeneration and tissue-resident muscle stem cell function in whole body Pparg null mice generated by epiblast-specific Cre/lox deletion (PpargΔ/Δ).

Fri Jul 13 00:00:00 UTC 2018

VEGF165b Modulates Endothelial VEGFR1-STAT3 Signaling Pathway and Angiogenesis in Human and Experimental Peripheral Arterial Disease.

Circulation research

Ganta VC,Choi M,Kutateladze A,Annex BH

RM5201 was used in flow cytometry to find that that vascular endothelial growth factor 165b prevents activation of vascular endothelial growth factor receptor 1-STAT3 signaling by vascular endothelial growth factor 165a

Fri Jan 20 00:00:00 UTC 2017

Anti-tumor immunity of BAM-SiPc-mediated vascular photodynamic therapy in a BALB/c mouse model.

Cellular & molecular immunology

Yeung HY,Lo PC,Ng DK,Fong WP

RM5201 was used in immunohistochemistry to show that that both cell-mediated and humoral adaptive immune components are involved in photodynamic therapy.

Wed Feb 01 00:00:00 UTC 2017

Polarized actin and VE-cadherin dynamics regulate junctional remodelling and cell migration during sprouting angiogenesis.

Nature communications

Cao J,Ehling M,März S,Seebach J,Tarbashevich K,Sixta T,Pitulescu ME,Werner AC,Flach B,Montanez E,Raz E,Adams RH,Schnittler H

RM5201 was used in Flow cytometry/Cell sorting to propose a model where polarized junction-associated intermittent lamellipodia formation drives directed cell migration and junctional remodelling during sprouting angiogenesis.

Wed Dec 20 00:00:00 UTC 2017

Loss of fibronectin from the aged stem cell niche affects the regenerative capacity of skeletal muscle in mice.

Nature medicine

Lukjanenko L,Jung MJ,Hegde N,Perruisseau-Carrier C,Migliavacca E,Rozo M,Karaz S,Jacot G,Schmidt M,Li L,Metairon S,Raymond F,Lee U,Sizzano F,Wilson DH,Dumont NA,Palini A,Fässler R,Steiner P,Descombes P,Rudnicki MA,Fan CM,von Maltzahn J,Feige JN,Bentzinger CF

RM5201 was used in flow cytometry to show that the loss of stem cell adhesion to fibronectin is a mechanism of aging

Mon Aug 01 00:00:00 UTC 2016

Kidney-specific Sonoporation-mediated Gene Transfer.

Molecular therapy : the journal of the American Society of Gene Therapy

Ishida R,Kami D,Kusaba T,Kirita Y,Kishida T,Mazda O,Adachi T,Gojo S

RM5201 was used in immunohistochemistry to elucidate sonoporation and its role in gene transfer in regards to kidneys

Mon Feb 01 00:00:00 UTC 2016

Protein MRI contrast agent with unprecedented metal selectivity and sensitivity for liver cancer imaging.

Proceedings of the National Academy of Sciences of the United States of America

Xue S,Yang H,Qiao J,Pu F,Jiang J,Hubbard K,Hekmatyar K,Langley J,Salarian M,Long RC,Bryant RG,Hu XP,Grossniklaus HE,Liu ZR,Yang JJ

Published figure using CD31 monoclonal antibody (Product # RM5201) in Immunofluorescence

Tue May 26 00:00:00 UTC 2015

Circulating progenitor and mature endothelial cells in deep vein thrombosis.

International journal of medical sciences

Alessio AM,Beltrame MP,Nascimento MC,Vicente CP,de Godoy JA,Silva JC,Bittar LF,Lorand-Metze I,de Paula EV,Annichino-Bizzacchi JM

RM5201 was used in flow cytometry to determine the contributions of mature circulating endothelial cells and circulating endothelial progenitor cells to deep vein thrombosis

Mon May 19 00:00:00 UTC 2014

Involvement of endothelial PECAM-1/CD31 in angiogenesis.

The American journal of pathology

DeLisser HM,Christofidou-Solomidou M,Strieter RM,Burdick MD,Robinson CS,Wexler RS,Kerr JS,Garlanda C,Merwin JR,Madri JA,Albelda SM

RM5201 was used in blocking or activating experiment and immunohistochemistry - frozen section to examine the effect of PECAM-1/ CD31 inhibition in rat and murine models of angiogenesis

Mon Sep 01 00:00:00 UTC 1997

生物信息学

蛋白别名: CD31; PECAM-1; Platelet endothelial cell adhesion molecule

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基因别名: C85791; Cd31; Pecam; PECAM-1; Pecam1

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UniProt ID: (Mouse) Q08481

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Entrez Gene ID: (Mouse) 18613

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功能

immunoglobulin receptor superfamily

CD31 Monoclonal Antibody (390), FITC

CD31 Antibody (RM5201) in Flow

产品信息

RM5201

免疫组化 (IHC)

免疫组化（冰冻） (IHC (F))

免疫细胞化学 (ICC/IF)

流式细胞分析 (Flow)

其他PubMed (Misc)

种属反应

已发表种属

宿主/亚型

分类

类型

克隆号

抗原

偶联物

激发/发射光谱

形式

纯化类型

保存液

内含物

保存条件

运输条件

RRID

靶标信息

How to use the Panel Builder

生物信息学

性能保障

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