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产品信息
PA5-88621
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 43-217 of human FCGR2B (NP_0039923)
偶联物
形式
Liquid
浓度
0.62 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2805037
产品详细信息
Positive Samples: Mouse spleen, Rat liver; Cellular Location: Cell membrane, Single-pass type I membrane protein
Immunogen sequence: TPAAPPKAVL KLEPQWINVL QEDSVTLTCR GTHSPESDSI QWFHNGNLIP THTQPSYRFK ANNNDSGEYT CQTGQTSLSD PVHLTVLSEW LVLQTPHLEF QEGETIVLRC HSWKDKPLVK VTFFQNGKSK KFSRSDPNFS IPQANHSHSG DYHCTGNIGY TLYSSKPVTI TVQAP
靶标信息
This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD32; CD32 receptor 2; CD32 receptor 2a; CD32 receptor 2b; CD32A; CDw32; Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32); Fc gamma receptor IIB; Fc gamma RIIB; Fc receptor, IgG, low affinity IIb; FC-gamma RII; fc-gamma RII-a; Fc-gamma RII-b; Fc-gamma-RII; fc-gamma-RIIa; Fc-gamma-RIIb; FcgammaRIIB; FcGR; FCGR2A1; FcRII; fcRII-a; fcRII-b; FGFR2B; IgG Fc receptor II beta; IgG Fc receptor II-b; Low affinity immunoglobulin gamma Fc region receptor II; Low affinity immunoglobulin gamma Fc region receptor II-b; Ly-17; Lymphocyte antigen 17
基因别名: AI528646; CD32; CD32B; F630109E10Rik; Fc[g]RII; FCG2; FcgammaRIIB2; FCGR2; Fcgr2a; FCGR2B; FcgRII; Fcr-2; Fcr-3; FCRII; IGFR2; Ly-17; Ly-m20; LyM-1
UniProt ID: (Human) P31994, (Rat) Q63203, (Mouse) P08101
Entrez Gene ID: (Human) 2213, (Rat) 289211, (Mouse) 14130
immune response
signal transduction
viral process
regulation of immune response
negative regulation of type I hypersensitivity
immune complex clearance
negative regulation of immunoglobulin production
negative regulation of inflammatory response to antigenic stimulus
negative regulation of acute inflammatory response to antigenic stimulus
negative regulation of humoral immune response mediated by circulating immunoglobulin
receptor-mediated endocytosis
phagocytosis, engulfment
defense response
cell surface receptor signaling pathway
response to bacterium
immunoglobulin mediated immune response
antigen processing and presentation of exogenous peptide antigen via MHC class II
negative regulation of B cell proliferation
response to estradiol
endocytic recycling
negative regulation of interleukin-10 production
negative regulation of neutrophil apoptotic process
mast cell activation
negative regulation of phagocytosis
positive regulation of phagocytosis
negative regulation of immune response
cellular response to molecule of bacterial origin
cellular response to lipopolysaccharide
intracellular signal transduction
