Invitrogen

CD46 Monoclonal Antibody (MM10)

产品信息

MA5-49014

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:50

免疫组化（冰冻） (IHC (F))

1:50

免疫细胞化学 (ICC/IF)

1:50

流式细胞分析 (Flow)

1:50

抑制试剂 (IA)

1:50

产品规格

种属反应

Mouse

宿主/亚型

Rat / IgG2a

分类

Monoclonal

类型

Antibody

克隆号

MM10

抗原

Mouse CD46-human Fc fusion protein

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

100 µg/mL

纯化类型

Protein G

保存液

PBS with 0.1% BSA

内含物

0.02% sodium azide

保存条件

4° C

运输条件

Wet ice

AB_3091085

产品详细信息

The monoclonal antibody MM10 recognizes membrane cofactor protein (MCP), also known as CD46.

靶标信息

CD46 (MCP, membrane cofactor protein) is a multifunctional cell surface transmembrane protein that binds and inactivates C3b and C4b complement fragments, regulates T cell-induced inflammatory responses by either inhibiting (CD46-1 isoform) or increasing (CD46-2 isoform) the contact hypersensitivity reaction. CD46 also serves as a receptor for several human pathogens (both bacteria and viruses), and its ligation alteres T lymphocyte polarization toward antigen-presenting cells or target cells, inhibiting lymphocyte function. CD46 is a protector of placental tissue and is also expressed on the inner acrosomal membrane of spermatozoa.

仅用于科研。不用于诊断过程。未经明确授权不得转售。