NeoBiotechnologies

CD51/Integrin V Monoclonal Antibody (ITGAV/1610)

查看其他6个CD51/CD61抗体

抗体检测数据 (1)

CD51/Integrin V Antibody in SDS-PAGE (SDS-PAGE)

CD51/Integrin V Antibody in SDS-PAGE (SDS-PAGE)

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CD51/Integrin V Antibody (3685-MSM1-P0) in SDS-PAGE

SDS-PAGE analysis Purified CD51/Integrin &V Mouse Monoclonal Antibody (ITGAV/1610). Confirmation of Purity and Integrity of Antibody.

CD51/Integrin V Antibody in SDS-PAGE (SDS-PAGE)

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CD51/Integrin V Antibody in SDS-PAGE (SDS-PAGE) — SDS-PAGE analysis Purified CD51/Integrin &V Mouse Monoclonal Antibody (ITGAV/1610). Confirmation of Purity and Integrity of Antibody.

产品信息

3685-MSM1-P0

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-2 µg/mL

-

免疫细胞化学 (ICC/IF)

1-2 µg/mL

-

流式细胞分析 (Flow)

1-2 µg/10^6 cells

-

酶联免疫吸附实验 (ELISA)

1-5 µg/mL

-

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1, kappa

分类

Monoclonal

类型

Antibody

克隆号

ITGAV/1610

抗原

Recombinant human full-length integrin alpha V beta 1 protein

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

200 µg/mL

纯化类型

Protein A/G

保存液

PBS, pH 7.4, with 0.05% BSA

内含物

0.05% sodium azide

保存条件

4° C, do not freeze

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

CD51 and CD61 molecules (alpha V and beta 3 integrins) form a complex. This complex binds vitronection at the RGD sequence and can also bind fibrinogen, von Willebrand factor, thrombospondin, fibronectin, osteopontin and collagen. Reacts with osteoclasts, placenta, melanoma cell lines and weakly with platelets.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: antigen CD61; antigen identified by monoclonal antibody L230; CD51; CD61; GPIIIa; integrin alpha V; integrin alpha-5 beta-3; Integrin alpha-V; integrin alphaVbeta3; integrin beta 3; Integrin beta-3; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51); integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); Platelet membrane glycoprotein IIIa; Vitronectin receptor; Vitronectin receptor subunit alpha

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基因别名: BDPLT16; BDPLT2; CD51; CD61; GP3A; GPIIIa; GT; ITGAV; ITGB3; MSK8; VNRA; VTNR

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UniProt ID: (Human) P06756, (Human) P05106

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Entrez Gene ID: (Human) 3685, (Human) 3690

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virus receptor activity opsonin binding fibronectin binding protease binding protein kinase C binding voltage-gated calcium channel activity protein binding coreceptor activity fibroblast growth factor binding C-X3-C chemokine binding insulin-like growth factor I binding neuregulin binding metal ion binding transforming growth factor beta binding extracellular matrix binding extracellular matrix protein binding protein disulfide isomerase activity platelet-derived growth factor receptor binding enzyme binding identical protein binding vascular endothelial growth factor receptor 2 binding cell adhesion molecule binding integrin

参与通路

angiogenesis antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent cell adhesion cell-matrix adhesion integrin-mediated signaling pathway positive regulation of cell proliferation negative regulation of macrophage derived foam cell differentiation negative regulation of lipid storage cell growth cell migration extracellular matrix organization positive regulation of cell migration cell-substrate adhesion negative regulation of lipid transport positive regulation of osteoblast proliferation heterotypic cell-cell adhesion substrate adhesion-dependent cell spreading endodermal cell differentiation apolipoprotein A-I-mediated signaling pathway apoptotic cell clearance negative regulation of low-density lipoprotein particle receptor biosynthetic process positive regulation of cell adhesion viral entry into host cell vascular endothelial growth factor receptor signaling pathway negative regulation of lipoprotein metabolic process regulation of phagocytosis leukocyte migration negative chemotaxis entry of symbiont into host cell by promotion of host phagocytosis ERK1 and ERK2 cascade calcium ion transmembrane transport extrinsic apoptotic signaling pathway in absence of ligand regulation of apoptotic cell clearance negative regulation of entry of bacterium into host cell negative regulation of extrinsic apoptotic signaling pathway positive regulation of protein phosphorylation positive regulation of endothelial cell proliferation platelet degranulation cell-substrate junction assembly blood coagulation positive regulation of endothelial cell migration smooth muscle cell migration platelet activation positive regulation of vascular endothelial growth factor receptor signaling pathway activation of protein kinase activity tube development wound healing regulation of bone resorption mesodermal cell differentiation positive regulation of peptidyl-tyrosine phosphorylation angiogenesis involved in wound healing platelet aggregation