Invitrogen

CD71 (Transferrin Receptor) Recombinant Rabbit Monoclonal Antibody (RM384)

CD71 (Transferrin Receptor) Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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CD71 (Transferrin Receptor) Antibody (MA5-33038) in IHC (P)

Immunohistochemistry analysis of formalin fixed and paraffin embedded human colon cancer tissue section usingCD71 (Transferrin Receptor) Recombinant Monoclonal antibody (Product # MA5-33038) at a dilution of 1:500.

CD71 (Transferrin Receptor) Antibody in Western Blot (WB)

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产品信息

MA5-33038

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:2,000

免疫组化（石蜡） (IHC (P))

1:250-1:500

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

RM384

抗原

A peptide corresponding to the internal region of human CD71.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.1 mg/mL

纯化类型

Protein A

保存液

PBS with 1% BSA, 50% glycerol

内含物

0.09% sodium azide

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

AB_2810131

产品详细信息

Specificity: reacts to Human CD71.

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

靶标信息

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.

仅用于科研。不用于诊断过程。未经明确授权不得转售。