Product References
Therapeutic targeting of PD-1/PD-L1 blockade by novel small-molecule inhibitors recruits cytotoxic T cells into solid tumor microenvironment.
Journal for immunotherapy of cancer
Acúrcio RC,Pozzi S,Carreira B,Pojo M,Gómez-Cebrián N,Casimiro S,Fernandes A,Barateiro A,Farricha V,Brito J,Leandro AP,Salvador JAR,Graça L,Puchades-Carrasco L,Costa L,Satchi-Fainaro R,Guedes RC,Florindo HF
MA5-16345 was used in Flow Cytometry, Immunohistochemistry (Paraffin) to identify a new promising family of small-molecule candidates that regulate the PD-L1/PD-1 signaling pathway, promoting an extensive infiltration of effector CD8 T cells to the tumor microenvironment.
Fri Jul 01 00:00:00 UTC 2022
Expression of programmed cell death ligand 1 (PD-L1) in advanced stage EBV-associated extranodal NK/T cell lymphoma is associated with better prognosis.
Virchows Archiv : an international journal of pathology
Kim WY,Jung HY,Nam SJ,Kim TM,Heo DS,Kim CW,Jeon YK
MA516345 was used in immunohistochemistry - paraffin section to assess programmed cell death 1 and programmed cell death ligand 1 expression in patients with extranodal natural killer/T cell lymphoma
Tue Nov 01 00:00:00 UTC 2016
Nontuberculous mycobacterial infection with concurrent IgG4-related lymphadenopathy.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
Liu TT,Weng SW,Wang MC,Huang WT
MA5-16345 was used in immunohistochemistry - paraffin section to study nontuberculous mycobacterial infection with mutual IgG4-related lymphadenopathy
Tue Mar 01 00:00:00 UTC 2016
Impact of early cART in the gut during acute HIV infection.
JCI insight
Deleage C,Schuetz A,Alvord WG,Johnston L,Hao XP,Morcock DR,Rerknimitr R,Fletcher JL,Puttamaswin S,Phanuphak N,Dewar R,McCune JM,Sereti I,Robb M,Kim JH,Schacker TW,Hunt P,Lifson JD,Ananworanich J,Estes JD
MA1-39566 was used in Immunohistochemistry to anaylse microbial translocation and systemic inflammation and immune activation in the GI tract in a cohort of Thai acute HIV-infected patients and determined the effect of early combination antiretroviral treatment (cART).
Thu Jul 07 00:00:00 UTC 2016
CUX1 modulates polarization of tumor-associated macrophages by antagonizing NF-κB signaling.
Oncogene
Kühnemuth B,Mühlberg L,Schipper M,Griesmann H,Neesse A,Milosevic N,Wissniowski T,Buchholz M,Gress TM,Michl P
MA5-16345 was used in immunocytochemistry to study the role of NFkB in the mechanism by which CUX1 regulates tumor-associated macrophage functionality
Thu Jan 08 00:00:00 UTC 2015
Tumor-Infiltrating Immune Cells Are Associated With Prognosis of Gastric Cancer.
Medicine
Liu K,Yang K,Wu B,Chen H,Chen X,Chen X,Jiang L,Ye F,He D,Lu Z,Xue L,Zhang W,Li Q,Zhou Z,Mo X,Hu J
MA5-16345 was used in immunohistochemistry - paraffin section to elucidate the prognosis of gastric cancer by tumor-infiltrating immune cells
Tue Sep 01 00:00:00 UTC 2015
Prognostic Implication of M2 Macrophages Are Determined by the Proportional Balance of Tumor Associated Macrophages and Tumor Infiltrating Lymphocytes in Microsatellite-Unstable Gastric Carcinoma.
PloS one
Kim KJ,Wen XY,Yang HK,Kim WH,Kang GH
MA5-16345 was used in immunohistochemistry - paraffin section to assess how proportional balance of tumor associated macrophages and tumor infiltrating lymphocytes in microsatellite-unstable gastric carcinoma is a prognostic indicator of M2 macrophages
Wed Jul 06 00:00:00 UTC 2016
Low intraprostatic DHT promotes the infiltration of CD8+ T cells in BPH tissues via modulation of CCL5 secretion.
Mediators of inflammation
Fan Y,Hu S,Liu J,Xiao F,Li X,Yu W,Cui Y,Sun M,Lv T,He Q,Jin J
MA5-16345 was used in immunohistochemistry to study the role of CCL5 secretion in the mechanism by which CD8(+) T-cell infiltration of benign prostatic hyperplasia tissue is enhanced by low dihydroxytestosterone levels
Thu Dec 18 00:00:00 UTC 2014
High infiltration of tumor-associated macrophages in triple-negative breast cancer is associated with a higher risk of distant metastasis.
OncoTargets and therapy
Yuan ZY,Luo RZ,Peng RJ,Wang SS,Xue C
MA1-39566 was used in immunohistochemistry - paraffin section to study the prognostic significance of the infiltration of tumor associate macrophages in patients with triple negative breast cancer
Thu Sep 04 00:00:00 UTC 2014
Prognostic implications of tumor-infiltrating FoxP3+ regulatory T cells and CD8+ cytotoxic T cells in microsatellite-unstable gastric cancers.
Human pathology
Kim KJ,Lee KS,Cho HJ,Kim YH,Yang HK,Kim WH,Kang GH
MA5-16345 was used in immunohistochemistry to study the prognostic value of FoxP3-positive regulatory T-cells and CD8-positive cytotoxic T-cells in gastric cancers with high microsatellite instability
Sat Feb 01 00:00:00 UTC 2014
Expression of CD8 is associated with non-common type morphology and outcome in pediatric anaplastic lymphoma kinase-positive anaplastic large cell lymphoma.
Haematologica
Abramov D,Oschlies I,Zimmermann M,Konovalov D,Damm-Welk C,Wössmann W,Klapper W
MA5-16345 was used in immunohistochemistry to study the prognostic value of CD8 expression in pediatric anaplastic lymphoma kinase-positive anaplastic large cell lymphoma and its association with non-common type morphology
Tue Oct 01 00:00:00 UTC 2013
Tumor-infiltrating lymphocytes, tumor characteristics, and recurrence in patients with early breast cancer.
American journal of clinical oncology
Kim ST,Jeong H,Woo OH,Seo JH,Kim A,Lee ES,Shin SW,Kim YH,Kim JS,Park KH
MA5-16345 was used in immunohistochemistry to study the relationships between tumor-infiltrating lymphocytes, breast cancer characteristics and tumor recurrence
Sat Jun 01 00:00:00 UTC 2013
T cell-activation in neuromyelitis optica lesions plays a role in their formation.
Acta neuropathologica communications
Pohl M,Kawakami N,Kitic M,Bauer J,Martins R,Fischer MT,Machado-Santos J,Mader S,Ellwart JW,Misu T,Fujihara K,Wekerle H,Reindl M,Lassmann H,Bradl M
MA5-16345 was used in immunohistochemistry to study the role of T-cell activation in the formation of neuromyelitis optica lesions
Tue Dec 24 00:00:00 UTC 2013
Lymphoid tissue damage in HIV-1 infection depletes naïve T cells and limits T cell reconstitution after antiretroviral therapy.
PLoS pathogens
Zeng M,Southern PJ,Reilly CS,Beilman GJ,Chipman JG,Schacker TW,Haase AT
MA1-39566 was used in immunohistochemistry to test if damage to the lymphoid tissue fibroblastic reticular cell network contributes to naive T cell loss during HIV-1 infection
Sun Jan 01 00:00:00 UTC 2012
Hepatitis C virus induces the expression of CCL17 and CCL22 chemokines that attract regulatory T cells to the site of infection.
Journal of hepatology
Riezu-Boj JI,Larrea E,Aldabe R,Guembe L,Casares N,Galeano E,Echeverria I,Sarobe P,Herrero I,Sangro B,Prieto J,Lasarte JJ
MA5-16345 was used in immunohistochemistry to study the role of CCL17 and CCL22 in Foxp3+ T regulatory cell accumulation at the site of HCV infection
Tue Mar 01 00:00:00 UTC 2011
CD8⁺ T cells with an intraepithelial phenotype upregulate cytotoxic function upon influenza infection in human lung.
The Journal of clinical investigation
Piet B,de Bree GJ,Smids-Dierdorp BS,van der Loos CM,Remmerswaal EB,von der Thüsen JH,van Haarst JM,Eerenberg JP,ten Brinke A,van der Bij W,Timens W,van Lier RA,Jonkers RE
MA1-39566 was used in immunohistochemistry to identify the role of CD103+CD8+ T cells in protection against respiratory viruses
Wed Jun 01 00:00:00 UTC 2011
Tumor-infiltrating lymphocytes predict response to anthracycline-based chemotherapy in estrogen receptor-negative breast cancer.
Breast cancer research : BCR
West NR,Milne K,Truong PT,Macpherson N,Nelson BH,Watson PH
MA1-39566 was used in immunohistochemistry to evaluate the prognostic value of tumor-infiltrating lymphocytes in the anthracycline-based chemotherapy
Mon Jun 25 00:00:00 UTC 2012
Study of cellular immune response against Hepatitis E virus (HEV).
Journal of viral hepatitis
Prabhu SB,Gupta P,Durgapal H,Rath S,Gupta SD,Acharya SK,Panda SK
MA1-39566 was used in immunohistochemistry to investigate the immunopathology of hepatitis E virus infection
Mon Aug 01 00:00:00 UTC 2011
Anaplastic large cell lymphoma with paraneoplastic leukocytosis: a clinicopathological analysis of five cases.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
Chang IW,Chen HK,Ma MC,Huang WT
MA5-16345 was used in immunohistochemistry to report on five cases of anaplastic large cell lymphoma with paraneoplastic leukocytosis
Tue Nov 01 00:00:00 UTC 2011
Intratumoral Immune Responses Can Distinguish New Primary and True Recurrence Types of Ipsilateral Breast Tumor Recurrences (IBTR).
Breast cancer : basic and clinical research
West NR,Panet-Raymond V,Truong PT,Alexander C,Babinszky S,Milne K,Ross LA,Loken S,Watson PH
MA1-39566 was used in immunohistochemistry - paraffin section to identify biomarkers to distinguish between true recurrence and new primary cases of ipsilateral breast tumor recurrence
Thu Jul 14 00:00:00 UTC 2011
Immune response to Mycobacterium tuberculosis infection in the parietal pleura of patients with tuberculous pleurisy.
PloS one
Caramori G,Lasagna L,Casalini AG,Adcock IM,Casolari P,Contoli M,Tafuro F,Padovani A,Chung KF,Barnes PJ,Papi A,Rindi G,Bertorelli G
MA1-39566 was used in immunohistochemistry to report the immune responses in the parietal pleura of patients with tuberculous pleurisy and compare them with nonspecific pleuritis
Tue Dec 06 00:00:00 UTC 2011
Spatial differences in the presence of FOXP3+ and GranzymeB+ T cells between the intra- and extravascular compartments in renal allograft vasculopathy.
PloS one
de Boer OJ,Teeling P,Jansen M,Ploegmakers H,van der Loos CM,Kummer JA,Florquin S,van der Wal AC
MA1-39566 was used in immunohistochemistry to investigate the differences of T cell subtypes between the intra- and extravascular compartments in renal allograft vasculopathy
Wed Apr 06 00:00:00 UTC 2011
Antagonism of TIM-1 blocks the development of disease in a humanized mouse model of allergic asthma.
The Journal of clinical investigation
Sonar SS,Hsu YM,Conrad ML,Majeau GR,Kilic A,Garber E,Gao Y,Nwankwo C,Willer G,Dudda JC,Kim H,Bailly V,Pagenstecher A,Rennert PD,Renz H
MA1-39566 was used in immunohistochemistry to investigate the role of the TIM-1 pathway in T cell activation and allergic asthma
Sun Aug 01 00:00:00 UTC 2010
Primary central nervous system peripheral T-cell lymphoma in a child.
Fetal and pediatric pathology
Gualco G,Wludarski S,Hayashi-Silva L,Medeiros Filho P,Veras G,Bacchi CE
MA5-16345 was used in immunohistochemistry to report on a case of primary central nervous system peripheral T-cell lymphoma in a child
Tue Sep 28 00:00:00 UTC 2010
Increased T-bet+ cytotoxic effectors and type I interferon-mediated processes in chronic graft-versus-host disease of the oral mucosa.
Blood
Imanguli MM,Swaim WD,League SC,Gress RE,Pavletic SZ,Hakim FT
MA1-39566 was used in immunohistochemistry to investigate the pathogenesis of chronic graft-versus-host disease
Thu Apr 09 00:00:00 UTC 2009
GMP-17-positive T-lymphocytes in renal tubules predict progression in early stages of IgA nephropathy.
Kidney international
van Es LA,de Heer E,Vleming LJ,van der Wal A,Mallat M,Bajema I,Bruijn JA,de Fijter JW
MA1-39566 was used in immunohistochemistry to investigate the predictive value of GMP-17-positive T-lymphocytes in IgA nephropathy
Sun Jun 01 00:00:00 UTC 2008
Selective expansion of influenza A virus-specific T cells in symptomatic human carotid artery atherosclerotic plaques.
Stroke
Keller TT,van der Meer JJ,Teeling P,van der Sluijs K,Idu MM,Rimmelzwaan GF,Levi M,van der Wal AC,de Boer OJ
MA1-39566 was used in immunohistochemistry to study the role of influenza A virus infection in atherothrombotic disease
Tue Jan 01 00:00:00 UTC 2008
Tumor-infiltrating T cells correlate with NY-ESO-1-specific autoantibodies in ovarian cancer.
PloS one
Milne K,Barnes RO,Girardin A,Mawer MA,Nesslinger NJ,Ng A,Nielsen JS,Sahota R,Tran E,Webb JR,Wong MQ,Wick DA,Wray A,McMurtrie E,Köbel M,Kalloger SE,Gilks CB,Watson PH,Nelson BH
MA1-39566 was used in immunohistochemistry to study autoantibodies and tumor-infiltrating T cells in epithelial ovarian cancer
Thu Dec 18 00:00:00 UTC 2008
Effect of melatonin and zinc on the immune response in experimental Toxoplasma retinochoroiditis.
Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde
Avunduk AM,Avunduk MC,Baltaci AK,Moğulkoç R
MA1-39566 was used in immunohistochemistry to investigate the impact of melatonin and zinc on immune and inflammatory responses to Toxoplasma retinochoroiditis in a rat model
Tue Nov 06 00:00:00 UTC 2007
Intrahepatic virus-specific IL-10-producing CD8 T cells prevent liver damage during chronic hepatitis C virus infection.
Hepatology (Baltimore, Md.)
Abel M,Sène D,Pol S,Bourlière M,Poynard T,Charlotte F,Cacoub P,Caillat-Zucman S
MA1-39566 was used in immunohistochemistry to investigate the role of CD8 T cells in the liver damage during chronic hepatitis C virus infection
Fri Dec 01 00:00:00 UTC 2006
