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CD8b Antibody (MA5-28438) in Flow
Flow cytometry of CD8b in red cell lysed bovine blood. Sample was incubated with CD8b monoclonal antibody (Product # MA5-28438) and gated on mononuclear cells. Figures are arranged as follows: A) RPE conjugated mouse anti bovine CD8b and FITC conjugated mouse IgG2b isotype control. B) RPE conjugated mouse anti bovine CD8b and FITC conjugated mouse anti bovine CD21.
产品信息
MA5-28438
产品规格
种属反应
Bovine
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
CC58
抗原
Bovine leucocytes
偶联物
激发/发射光谱
565/576 nm
查看光谱
形式
Lyophilized
浓度
Conc. not determined
纯化类型
Protein G
保存液
PBS with 5% sucrose, 1% BSA
内含物
0.09% sodium azide
保存条件
4° C, store in dark, DO NOT FREEZE!
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2745400
产品详细信息
This antibody recognizes an epitope associated with the bovine CD8 beta chain. CD8 is usually expressed as an alpha/beta heterodimer. Further, this antibody has been successfully used for the immunohistochemical detection of CD8 on formalin fixed, paraffin embedded placental tissue from water buffalo.
Reconstitute by adding 1 mL distilled water.
靶标信息
The CD8B antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
How to use the Panel Builder
Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.
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生物信息学
蛋白别名: CD8; CD8a; CD8alpha; CD8b antigen; CD8beta; Leu-2; MAL; p32
Entrez Gene ID: (Bovine) 508633
