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CDA Antibody (PA5-95616) in IHC (P)
Immunohistochemistry analysis of CDA in paraffin-embedded human intestinal cancer tissue. Antigen retrieval was performed on the tissue using citrate buffer (pH 6, 20 min) and blocked with 10% goat serum. Samples were incubated with CDA polyclonal antibody (Product # PA5-95616) at a 1 µg/mL dilution, followed by biotinylated goat anti-rabbit IgG (30 min, 37°C), and developed with Strepavidin-Biotin-Complex ... View More
Product Details
PA5-95616
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence of human CDA (MAQKRPACTLKPECVQQLLVCSQEAKK).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2807418
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human Hela whole cell. IHC: human intestinal cancer tissue, human lung cancer tissue, mouse intestine tissue, human mammary cancer tissue, human tonsil tissue, rat brain tissue, rat intestine tissue.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
This gene encodes an enzyme involved in pyrimidine salvaging. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in this gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cytidine aminohydrolase; Cytidine deaminase; cytosine nucleoside deaminase; EC 3.5.4.5; small cytidine deaminase
Gene Aliases: 2210401N16Rik; CDA; CDD
UniProt ID: (Human) P32320, (Mouse) P56389
Entrez Gene ID: (Human) 978, (Mouse) 72269, (Rat) 362638
cytidine deamination
negative regulation of cell growth
negative regulation of nucleotide metabolic process
protein homotetramerization
cell surface receptor signaling pathway
pyrimidine-containing compound salvage
cytosine metabolic process
pyrimidine nucleoside salvage
response to cycloheximide
cellular response to external biotic stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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