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CDC42 Antibody (PA5-80456) in WB
Western Blot using CDC42 Polyclonal Antibody (Product # PA5-80456) at 1:500 dilution. Lane A: HepG2 Whole Cell Lysate, Lane B: Jurkat Whole Cell Lysate, Lane C: Hela Whole Cell Lysate. Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG H&L (DyLight™ 800) at 1:10,000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size: 21 kDa. Observed band size: 21 kDa. (We are unsure of the identity of these extra bands).
产品信息
PA5-80456
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human CDC42 protein (Met1-Cys188)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2787770
产品详细信息
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human CDC42.
靶标信息
Rac1 is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for the Rac1 gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cell division control protein 42 homolog; dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD)); dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein, 25kD)); G25K GTP-binding protein; growth-regulating protein; GTP binding protein, 25kDa; GTP-binding protein; RP1-224A6.5; small GTP binding protein CDC42
基因别名: CDC42; CDC42Hs; G25K; TKS
UniProt ID: (Human) P60953
Entrez Gene ID: (Human) 998
GTPase activity
protein binding
GTP binding
protein kinase binding
GTP-dependent protein binding
mitogen-activated protein kinase kinase kinase binding
thioesterase binding
apolipoprotein A-I receptor binding
identical protein binding
Rho GDP-dissociation inhibitor binding
ubiquitin protein ligase activity
small GTPase
sprouting angiogenesis
cardiac conduction system development
keratinocyte development
Golgi organization
regulation of mitotic nuclear division
nuclear migration
establishment or maintenance of cell polarity
small GTPase mediated signal transduction
blood coagulation
positive regulation of gene expression
negative regulation of gene expression
protein ubiquitination
substantia nigra development
actin cytoskeleton organization
macrophage differentiation
positive regulation of cell growth
hair follicle morphogenesis
positive regulation of pseudopodium assembly
T cell costimulation
negative regulation of protein complex assembly
keratinization
regulation of protein stability
positive regulation of cytokinesis
positive regulation of peptidyl-serine phosphorylation
adherens junction organization
cellular protein localization
establishment or maintenance of apical/basal cell polarity
multicellular organism growth
dendritic cell migration
Fc-gamma receptor signaling pathway involved in phagocytosis
negative regulation of epidermal growth factor receptor signaling pathway
regulation of protein catabolic process
regulation of protein heterodimerization activity
positive regulation of neuron apoptotic process
positive regulation of phosphatidylinositol 3-kinase activity
positive regulation of DNA replication
regulation of protein kinase activity
positive regulation of JNK cascade
filopodium assembly
vascular endothelial growth factor receptor signaling pathway
ephrin receptor signaling pathway
neuron fate determination
actin filament bundle assembly
regulation of small GTPase mediated signal transduction
positive regulation of muscle cell differentiation
regulation of filopodium assembly
establishment of Golgi localization
positive regulation of synapse structural plasticity
regulation of attachment of spindle microtubules to kinetochore
heart contraction
canonical Wnt signaling pathway
Wnt signaling pathway, planar cell polarity pathway
positive regulation of epithelial cell proliferation involved in lung morphogenesis
submandibular salivary gland formation
epithelial-mesenchymal cell signaling
hair follicle placode formation
positive regulation of hair follicle cell proliferation
organelle transport along microtubule
actin filament branching
epithelial cell-cell adhesion
positive regulation of intracellular protein transport
positive regulation of substrate adhesion-dependent cell spreading
