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产品信息
988-MSM1-P1ABX
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
PCRP-CDC5L-2C6
抗原
Recombinant fragment (around aa 1-148) of human CDC5L protein.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A/G
保存液
PBS
内含物
no preservative
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Dry ice (international)
产品详细信息
Positive Control:HeLa cells. Ubiquitously expressed in both fetal and adult tissues.
Cellular Location: Nucleus. Cytoplasm.
靶标信息
The protein encoded by this gene shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. This protein has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CDC5 cell division cycle 5-like; Cdc5-like protein; Cdc5-related protein; Cell division cycle 5-like protein; dJ319D22.1 (CDC5-like protein); hCDC5; Pombe cdc5-related protein
基因别名: CDC5; CDC5-LIKE; CDC5L; CEF1; dJ319D22.1; KIAA0432; PCDC5RP
UniProt ID: (Human) Q99459
Entrez Gene ID: (Human) 988
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II transcription factor recruiting
transcription corepressor binding
DNA binding
protein binding
protein phosphatase 1 binding
protein kinase binding
leucine zipper domain binding
sequence-specific DNA binding
transcription regulatory region DNA binding
poly(A) RNA binding
WD40-repeat domain binding
mitotic cell cycle
mRNA splicing, via spliceosome
DNA repair
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
cell differentiation
cellular response to fibroblast growth factor stimulus
cellular response to interleukin-2
signal transduction involved in DNA damage checkpoint
cellular response to wortmannin
cellular response to nerve growth factor stimulus
cellular response to prolactin
