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CDH13 Antibody (H00001012-D01P) in WB
Western Blot analysis of CDH13 expression in transfected 293T cell line (H00001012-T02) by CDH13 MaxPab polyclonal antibody.
Lane 1: CDH13 transfected lysate(78.30 KDa).
Lane 2: Non-transfected lysate.
Lane 1: CDH13 transfected lysate(78.30 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00001012-D01P
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CDH13 (NP_001248.1, 1 a.a. approximately 713 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MQPRTPLVLC VLLSQVLLLT SAEDLDCTPG FQQKVFHINQ PAEFIEDQSI LNLTFSDCKG NDKLRYEVSS PYFKVNSDGG LVALRNITAV GKTLFVHART PHAEDMAELV IVGGKDIQGS LQDIFKFART SPVPRQKRSI VVSPILIPEN QRQPFPRDVG KVVDSDRPER SKFRLTGKGV DQEPKGIFRI NENTGSVSVT RTLDREVIAV YQLFVETTDV NGKTLEGPVP LEVIVIDQND NRPIFREGPY IGHVMEGSPT GTTVMRMTAF DADDPATDNA LLRYNIRQQT PDKPSPNMFY IDPEKGDIVT VVSPALLDRE TLENPKYELI IEAQDMAGLD VGLTGTATAT IMIDDKNDHS PKFTKKEFQA TVEEGAVGVI VNLTVEDKDD PTTGAWRAAY TIINGNPGQS FEIHTNPQTN EGMLSVVKPL DYEISAFHTL LIKVENEDPL VPDVSYGPSS TATVHITVLD VNEGPVFYPD PMMVTRQEDL SVGSVLLTVN ATDPDSLQHQ TIRYSVYKDP AGWLNINPIN GTVDTTAVLD RESPFVDNSV YTALFLAIDS GNPPATGTGT LLITLEDVND NAPFIYPTVA EVCDDAKNLS VVILGASDKD LHPNTDPFKF EIHKQAVPDK VWKISKINNT HALVSLLQNL NKANYNLPIM VTDSGKPPMT NITDLRVQVC SCRNSKVDCN AAGALRFSLP SVLLLSLFSL ACL
靶标信息
The protein encoded by this gene has a C-terminal domain with tRNA 3 processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CAD13; cadherin 13, H-cadherin (heart); Cadherin-13; CD39 antigen-like 3; CD39-like 3; CD39L3; ecto-apyrase 3; ecto-ATPase 3; ecto-ATPDase 3; H-cadherin; H-cadherin (heart); HB6; Heart cadherin; heart-cadherin; NTPDase 3; NTPDase-3; P105; T cad; T Cadherin; T-cad; T-cadherin; Truncated cadherin; truncated-cadherin
基因别名: CDH13; CDHH; P105
UniProt ID: (Human) P55290
Entrez Gene ID: (Human) 1012
mitotic cell cycle
positive regulation of endothelial cell proliferation
positive regulation of cell-matrix adhesion
sprouting angiogenesis
homophilic cell adhesion via plasma membrane adhesion molecules
negative regulation of cell adhesion
Rho protein signal transduction
negative regulation of cell proliferation
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
Rac protein signal transduction
lamellipodium assembly
regulation of endocytosis
positive regulation of cell migration
adherens junction organization
regulation of epidermal growth factor receptor signaling pathway
endothelial cell migration
keratinocyte proliferation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of smooth muscle cell proliferation
positive regulation of calcium-mediated signaling
positive regulation of positive chemotaxis
localization within membrane
low-density lipoprotein particle mediated signaling
