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CDK5RAP1 Antibody (PA5-90755) in IHC (P)
Immunohistochemistry analysis of CDK5RAP1 in paraffin-embedded human colon carcinoma. Samples were incubated with CDK5RAP1 Polyclonal antibody (Product # PA5-90755) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
产品信息
PA5-90755
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human CDK5RAP1 (NP_0574922)
偶联物
形式
Liquid
浓度
3.73 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2806223
产品详细信息
Immunogen sequence: MHPLQCVLQV QRSLGWGPLA SVSWLSLRMC RAHSSLSSTM CPSPERQEDG ARKDFSSRLA AGPTFQHFLK SASAPQEKLS SEVEDPPPYL MMDELLGRQR KVYLETYGCQ MNVNDTEIAW SILQKSGYLR TSNLQEADVI LLVTCSIREK AEQTIWNRLH QLKALKTRRP RSRVPLRIGI LGCMAERLKE EILNREKMVD ILAGPDAYRD LPRLLAVAES GQQAANVLLS LDETYADVMP VQTSASATSA FVSIMRGCDN MCSYCIVPFT RGRERSRPIA SILEEVKKLS EQGLKEVTLL GQNVNSFRDN SEVQFNSAVP TNLSRGFTTN YKTKQGGLRF AHLLDQVSRV; Positive Samples: A-549, Mouse thymus
靶标信息
Neuronal CDC2-like kinase, which is involved in the regulation of neuronal differentiation, is composed of a catalytic subunit, CDK5, and an activating subunit, p25NCK5A. The protein encoded by this gene binds to p25NCK5A and therefore may be involved in neuronal differentiation. Multiple transcript variants exist for this gene, but the full-length natures of only two have been determined.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CDK5 activator-binding protein C42; CDK5 regulatory subunit-associated protein 1; CDK5RAP1.3; CDK5RAP1.4; Mitochondrial tRNA methylthiotransferase CDK5RAP1; mt-tRNA-2-methylthio-N6-dimethylallyladenosine synthase; mt-tRNA-N6-(dimethylallyl)adenosine(37) methylthiotransferase
基因别名: 2310066P17Rik; C20orf34; C42; CDK5RAP1; CGI-05; HSPC167
UniProt ID: (Human) Q96SZ6, (Rat) Q9JLH6, (Mouse) Q8BTW8
Entrez Gene ID: (Human) 51654, (Rat) 252827, (Mouse) 66971
brain development
tRNA methylthiolation
regulation of neuron differentiation
negative regulation of cyclin-dependent protein serine/threonine kinase activity
regulation of cyclin-dependent protein serine/threonine kinase activity
tRNA modification
cell proliferation
regulation of protein kinase activity
RNA modification
macromolecule modification
