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产品信息
PA5-55717
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2639612
产品详细信息
Immunogen sequence: GDFGVEAVSE GTDSGISAEA AGIDWGIFPE SDSKDPGGDG IDWGDDAVAL QITVLEAGTQ APEGVARGPD ALTLLEYTET RNQFLDELME LEIFLAQRAV ELSEEADVLS VSQFQ
Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 79%.
靶标信息
This gene encodes a protein that has been reported to function in signaling pathways governing transcriptional regulation and cell cycle progression. It may play a role in tumorigenesis and metastasis. A pseudogene of this gene is located on the long arm of chromosome 20. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, May 2013].
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生物信息学
蛋白别名: CDK5 activator-binding protein C53; CDK5 regulatory subunit associated protein IC53-2; CDK5 regulatory subunit-associated protein 3; IC53-2; ischemic heart CDK5 activator-binding protein C53; LXXLL/leucine-zipper-containing ARF-binding protein; LXXLL/leucine-zipper-containing ARFbinding protein; Protein HSF-27
基因别名: C53; CDK5RAP3; HSF-27; IC53; LZAP; MST016; MSTP016; OK/SW-cl.114; PP1553
UniProt ID: (Human) Q96JB5
Entrez Gene ID: (Human) 80279
regulation of cyclin-dependent protein serine/threonine kinase activity
negative regulation of protein phosphorylation
mitotic G2 DNA damage checkpoint
brain development
cell proliferation
regulation of phosphatase activity
apoptotic nuclear changes
endoplasmic reticulum unfolded protein response
positive regulation of protein ubiquitination
negative regulation of NF-kappaB transcription factor activity
negative regulation of MAP kinase activity
negative regulation of protein kinase activity by regulation of protein phosphorylation
mitotic G2/M transition checkpoint
regulation of neuron differentiation
positive regulation of transcription from RNA polymerase II promoter
protein ufmylation
negative regulation of protein serine/threonine kinase activity
positive regulation of protein localization to nucleus
positive regulation of signal transduction by p53 class mediator
negative regulation of cellular protein catabolic process
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
