Invitrogen

CDSN Polyclonal Antibody

CDSN Antibody in Immunohistochemistry (IHC)

图: 1 / 7

CDSN Antibody (PA5-62936) in IHC

Immunohistochemical staining of CDSN in human cerebral cortex, colon, kidney and skin using CDSN Polyclonal Antibody (Product # PA5-62936) (A) shows similar protein distribution across tissues to an independent CDSN Polyclonal Antibody (B).

Product Image Gallery

CDSN Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of CDSN demonstrates antibody specificity. Immunohistochemical analysis of CDSN using anti-CDSN Polyclonal Antibody (Product # PA5-62936), shows significant staining of CDSN in human skin and shows minimal or weak staining in human pancreas tissues. The relative expression levels of CDSN within each tissue is shown using RNA-Seq. {RE}

产品信息

PA5-62936

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

1:200-1:500

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human CDSN. Recombinant protein control fragment (Product #RP-103177).

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2639630

产品详细信息

Immunogen sequence: SSSSSQSSGK IILQPCGSKS SSSGHPCMSV SSLTLTGGPD GSPHPDPSAG AKPCGSSSAG KIPCRSIRDI LAQ

Highest antigen sequence identity to the following orthologs: Mouse - 66%, Rat - 35%.

靶标信息

This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。