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NeoBiotechnologies
CDX2/Caudal Type Homeobox 2 Recombinant Mouse Monoclonal Antibody (rCDX2, 1690)
产品信息
1045-MSM6-P1
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
rCDX2, 1690
抗原
Recombinant fragment (around aa150-249) of human CDX2 protein
偶联物
形式
Liquid
浓度
200 µg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.4, with 0.05% BSA
内含物
0.05% sodium azide
保存条件
4° C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.
靶标信息
The product of this gene is an epsilon subunit of coatomer protein complex. Coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles. It is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Coatomer complex consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: caudal type homeo box transcription factor 2; caudal type homeobox transcription factor 2; Caudal-type homeobox protein 2; CDX-3; HGNC:1806; Homeobox protein CDX-2; homeobox protein miniCDX2
基因别名: CDX-3; CDX2; CDX2/AS; CDX3
UniProt ID: (Human) Q99626
Entrez Gene ID: (Human) 1045
RNA polymerase II distal enhancer sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
homeodomain transcription factor
negative regulation of transcription from RNA polymerase II promoter
blood vessel development
trophectodermal cell differentiation
transcription from RNA polymerase II promoter
positive regulation of cell proliferation
endosome to lysosome transport
organ morphogenesis
anterior/posterior axis specification
regulation of somitogenesis
cell differentiation
somatic stem cell population maintenance
establishment or maintenance of epithelial cell apical/basal polarity
positive regulation of cell differentiation
positive regulation of transcription, DNA-templated
intestinal epithelial cell differentiation
labyrinthine layer development
