Invitrogen

CEACAM1/CEACAM3/CEACAM6 Monoclonal Antibody (YTH71.3)

CEACAM1/CEACAM3/CEACAM6 Antibody in Flow Cytometry (Flow)

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CEACAM1/CEACAM3/CEACAM6 Antibody (MA1-90031) in Flow

Flow Cytometry analysis of CD45RB was performed in human peripheral blood granulocytes using CD45RB Monoclonal Antibody (MEM55) (Product # MA1-90840).

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产品信息

MA1-90031

应用

建议稀释比

已发表文章

免疫组化（冰冻） (IHC (F))

Assay-dependent

流式细胞分析 (Flow)

10 µL for 10^6 cells in 100 µL

产品规格

种属反应

Human, Non-human primate, Rhesus monkey

宿主/亚型

Rat / IgG2a

分类

Monoclonal

类型

Antibody

克隆号

YTH71.3

抗原

Human lymphocytes

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein G

保存液

PBS

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2260310

产品详细信息

MA1-90031 detects CD66a, CD66c + CD66d from non-human primate, human samples.

靶标信息

This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: antigen CD66; BGP-1; Biliary glycoprotein 1; Carcinoembryonic antigen CGM1; carcinoembryonic antigen gene family member 1; Carcinoembryonic antigen-related cell adhesion molecule 1; carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein); Carcinoembryonic antigen-related cell adhesion molecule 3; carcinoembryonic antigen-related cell adhesion molecule 5-like; Carcinoembryonic antigen-related cell adhesion molecule 6; carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen); CD66a; CD66a antigen; CD66c; CD66d; CD66d antigen; Cluster of Differentiation 66c; Non-specific crossreacting antigen; nonspecific cross-reacting antigen; Normal cross-reacting antigen; pan CEACAM

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基因别名: BGP; BGP1; BGPI; CD66c; CD66D; CEA; CEACAM1; CEACAM3; CEACAM6; CEAL; CGM1; NCA; W264; W282

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UniProt ID: (Human) P13688, (Human) P40198, (Human) P40199

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Entrez Gene ID: (Human) 634, (Human) 1084, (Human) 4680, (Rhesus monkey) 707824

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功能

molecular_function actin binding protein binding bile acid transmembrane transporter activity kinase binding protein phosphatase binding filamin binding protein homodimerization activity protein dimerization activity protein tyrosine kinase binding

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