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CELSR3/Flamingo Homolog 1 Antibody (A305-188A) in IP
Detection of human CELSR3 by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from HeLa cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-CELSR3 antibody (Product # A305-188A) (lot 1) used for IP at 6 µg per reaction. CELSR3 was also immunoprecipitated by rabbit anti-CELSR3 antibody BL20560. For blotting immunopr... View More
产品信息
A305-188A
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 3262 to 3312 of human Cadherin EGF LAG seven-pass G-type receptor 3.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
phosphate/tris citrate, pH 7-8
内含物
0.09% sodium azide
保存条件
4° C
运输条件
Wet ice
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat
靶标信息
CELSR3 is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: adhesion G protein-coupled receptor C3; anchor protein; Cadherin EGF LAG seven-pass G-type receptor 3; Cadherin family member 11; cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila); EGF-like protein 1; EGF-like-domain, multiple 1; Epidermal growth factor-like protein 1; Flamingo homolog 1; hFmi1; Megf3; Multiple EGF-like domains protein 2; Multiple epidermal growth factor-like domains protein 2
基因别名: ADGRC3; CDHF11; CELSR3; EGFL1; FMI1; HFMI1; KIAA0812; MEGF2; RESDA1
UniProt ID: (Human) Q9NYQ7
Entrez Gene ID: (Human) 1951
neuron migration
regulation of protein phosphorylation
homophilic cell adhesion via plasma membrane adhesion molecules
G-protein coupled receptor signaling pathway
axonal fasciculation
regulation of protein localization
dopaminergic neuron axon guidance
serotonergic neuron axon guidance
cilium assembly
Wnt signaling pathway, planar cell polarity pathway
