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CEP120 Antibody (PA5-109513) in WB
Western blot analysis of CEP120 in extracts of various cell lines. Samples were incubated with CEP120 Polyclonal antibody (Product # PA5-109513) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-109513
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human CEP120 (NP_694955.2).
偶联物
形式
Liquid
浓度
0.7 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2854924
产品详细信息
Immunogen sequence: MVSKSDQLLI VVSILEGRHF PKRPKHMLVV EAKFDGEQLA TDPVDHTDQP EFATELAWEI DRKALHQHRL QRTPIKLQCF ALDPVTSAKE TIGYIVLDLR TAQETKQAPK WYQLLSNKYT KFKSEIQISI ALETDTKPPV DSFKAKGAPP RDGKVPAILA GLDPRDIVAV LNEEGGYHQI GPAEYCTDSF IMSVTIAFAT QLEQLIPCTM KLPERQPEFF FYYSLLGNDV TNEPFNDLIN PNFEPERASV RIRSSVEILR VYLALQSKLQ
靶标信息
This gene encodes a protein that functions in the microtubule-dependent coupling of the nucleus and the centrosome. A similar protein in mouse plays a role in both interkinetic nuclear migration, which is a characteristic pattern of nuclear movement in neural progenitors, and in neural progenitor self-renewal. Mutations in this gene are predicted to result in neurogenic defects. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: centrosomal protein 120kDa; Centrosomal protein of 120 kDa; Cep120; coiled-coil domain containing 100; Coiled-coil domain-containing protein 100
基因别名: A230075C01; AU016693; CCDC100; CEP120; RGD1565619; SRTD13
UniProt ID: (Human) Q8N960, (Mouse) Q7TSG1
Entrez Gene ID: (Human) 153241, (Rat) 307302, (Mouse) 225523
microtubule cytoskeleton organization
cell proliferation
cerebral cortex development
neurogenesis
interkinetic nuclear migration
astral microtubule organization
regulation of protein localization
regulation of microtubule-based process
positive regulation of centrosome duplication
positive regulation of cilium assembly
centrosome organization
