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产品信息
MA5-30222
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
034
抗原
Recombinant Human CER1/Cerberus 1 Protein (Met1-Ala267)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2785982
产品详细信息
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Human CER1/Cerberus 1.
靶标信息
This gene encodes a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein antagonists that can bind directly to BMPs and inhibit their activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cerberus; cerberus 1, cysteine knot superfamily, homolog; cerberus-related 1; Cerberus-related protein; DAN domain family member 4; MGC119894; MGC119895; MGC96951
基因别名: CER1; DAND4
UniProt ID: (Human) O95813
Entrez Gene ID: (Human) 9350
ureteric bud development
growth plate cartilage chondrocyte proliferation
gastrulation
nervous system development
negative regulation of cell proliferation
anterior/posterior axis specification
anterior/posterior pattern specification
signal transduction involved in regulation of gene expression
negative regulation of Wnt signaling pathway
bone mineralization
BMP signaling pathway
negative regulation of BMP signaling pathway
negative regulation of activin receptor signaling pathway
sequestering of BMP in extracellular matrix
cell migration involved in gastrulation
determination of dorsal identity
determination of heart left/right asymmetry
cellular response to BMP stimulus
negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry
negative regulation of mesoderm development
