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产品信息
PA5-64074
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2639773
产品详细信息
Immunogen sequence: TAVTMGKVTK SMAGVVKSMD ATLKTMNLEK ISALMDKFEH QFETLDVQTQ QMEDTMSSTT
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 97%.
靶标信息
CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A, is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 ).
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生物信息学
蛋白别名: Charged multivesicular body protein 1b; CHMP1.5; CHMP1b; chromatin modifying protein 1B; Chromatin-modifying protein 1b; vacuolar protein sorting 46-2; Vacuolar protein sorting-associated protein 46-2; Vps46-2
基因别名: C10orf2; C18-ORF2; C18orf2; CHMP1.5; CHMP1B; hVps46-2; Vps46-2; Vps46B
UniProt ID: (Human) Q7LBR1
Entrez Gene ID: (Human) 57132
cell separation after cytokinesis
nucleus organization
vacuolar transport
mitotic metaphase plate congression
regulation of centrosome duplication
protein transport
multivesicular body assembly
viral budding via host ESCRT complex
establishment of protein localization
cell division
regulation of mitotic spindle assembly
ESCRT III complex disassembly
