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CHMP2A Antibody (PA5-106311) in ICC/IF
Immunofluorescent analysis of CHMP2A in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and CHMP2A polyclonal antibody (Product # PA5-106311) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
产品信息
PA5-106311
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CHMP2A(Accession O43633), corresponding to amino acid residues E158-A208.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2853988
产品详细信息
Antibody detects endogenous levels of total CHMP2A.
靶标信息
CHMP2A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A is required for both MVB formation and regulation of cell cycle progression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Charged multivesicular body protein 2a; CHMP2a; chromatin modifying protein 2A; Chromatin-modifying protein 2a; mVps2; putative breast adenocarcinoma marker (32kD); Putative breast adenocarcinoma marker BC-2; Vacuolar protein sorting-associated protein 2; Vacuolar protein sorting-associated protein 2-1; vacuolar protein-sorting-associated protein 2; VPS2 homolog A; Vps2-1
基因别名: 1500016L11Rik; BC-2; BC2; CHMP2; CHMP2A; RGD1305050; VPS2; VPS2A
UniProt ID: (Human) O43633, (Mouse) Q9DB34
Entrez Gene ID: (Human) 27243, (Rat) 365191, (Mouse) 68953
cell separation after cytokinesis
autophagy
nucleus organization
mitotic metaphase plate congression
membrane invagination
exit from mitosis
regulation of centrosome duplication
protein transport
endosomal transport
viral life cycle
nuclear envelope reassembly
multivesicular body assembly
viral budding via host ESCRT complex
establishment of protein localization
regulation of viral process
protein polymerization
protein homooligomerization
protein heterooligomerization
negative regulation of cell death
regulation of mitotic spindle assembly
positive regulation of viral release from host cell
positive regulation of exosomal secretion
negative regulation of centriole elongation
ESCRT III complex disassembly
vacuolar transport
transport
