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CHMP2B Antibody (PA5-31128) in IHC (P)
CHMP2B Polyclonal Antibody detects CHMP2B protein at cytoplasm on human breast carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human breast carcinoma. CHMP2B Polyclonal Antibody (Product # PA5-31128) diluted at 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
产品信息
PA5-31128
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 19 and 213 of Human CHMP2B
偶联物
形式
Liquid
浓度
0.59 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 1% BSA, 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2548602
产品详细信息
Recommended positive controls: 293T, A431.
Predicted reactivity: Mouse (100%), Xenopus laevis (93%), Pig (99%), Chicken (95%), Rhesus Monkey (99%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
CHMP2B, also known as CHMP2.5 or vacuolar protein-sorting-associated protein 2-2, is a 213 amino acid cytosolic protein. Widely expressed in brain, heart, skeletal muscle, small intestine, pancreas, lung, placenta and leukocytes, CHMP2B associates directly with CHMP2A and vps4 for the disassembly of the ESCRT-III complex. Defects in the gene encoding CHMP2B have been shown to cause chromosome 3-linked frontotemporal dementia (FTD3).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Charged multivesicular body protein 2b; CHMP family; CHMP2.5; CHMP2b; chromatin modifying protein 2B; Chromatin-modifying protein 2b; hVps2-2; Vacuolar protein sorting-associated protein 2-2; vacuolar protein-sorting-associated protein 2-2; VPS2 homolog B; Vps2-2
基因别名: ALS17; CGI-84; CHMP2.5; CHMP2B; DMT1; VPS2-2; VPS2B
UniProt ID: (Human) Q9UQN3
Entrez Gene ID: (Human) 25978
cell separation after cytokinesis
autophagy
nucleus organization
endosome organization
mitotic metaphase plate congression
regulation of centrosome duplication
protein transport
endosomal transport
viral life cycle
multivesicular body assembly
viral budding via host ESCRT complex
cognition
neuron cellular homeostasis
multivesicular body sorting pathway
cell-cell adhesion
regulation of mitotic spindle assembly
positive regulation of viral release from host cell
ESCRT III complex disassembly
