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产品信息
PA5-114255
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the C-terminal region of Mouse Chmp4c (aa 146-195).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2884769
产品详细信息
Immunogen sequence: SEAFSQRVQF ADGFDEAELL AELEELEQEE LNKKMTSLEL PNVPSSSLPA
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted homology: Cow: 100%; Dog: 92%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 92%; Zebrafish: 92%
靶标信息
CHMP4C belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A, is required for both MVB formation and regulation of cell cycle progression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Charged multivesicular body protein 4c; CHMP4c; chromatin modifying protein 4C; Chromatin-modifying protein 4c; Snf7 homologue associated with Alix 3
基因别名: 2010012P02Rik; 2210015K02Rik; 2310010I16Rik; Chmp4c; Shax3; Snf7-3
UniProt ID: (Mouse) Q9D7F7
Entrez Gene ID: (Mouse) 66371
cell separation after cytokinesis
transport
nucleus organization
vacuolar transport
mitotic metaphase plate congression
bioluminescence
abscission
regulation of centrosome duplication
protein transport
negative regulation of cytokinesis
regulation of viral process
ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway
regulation of mitotic spindle assembly
positive regulation of viral release from host cell
