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产品信息
PA5-54889
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2639780
产品详细信息
Immunogen sequence: MSKLGKFFKG GGSSKSRAAP SPQEALVRLR ETEEMLGKKQ EYLENRIQRE IALAKKHGTQ N
Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 84%.
靶标信息
CHMP4C belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A, is required for both MVB formation and regulation of cell cycle progression.
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生物信息学
蛋白别名: Charged multivesicular body protein 4c; CHMP4c; chromatin modifying protein 4C; Chromatin-modifying protein 4c; hSnf7-3; hVps32-3; SNF7 homolog associated with Alix 3; Snf7 homologue associated with Alix 3; SNF7-3; Vacuolar protein sorting-associated protein 32-3; Vps32-3
基因别名: CHMP4C; SHAX3; SNF7-3; VPS32C
UniProt ID: (Human) Q96CF2
Entrez Gene ID: (Human) 92421
cell separation after cytokinesis
autophagy
nucleus organization
mitotic metaphase plate congression
abscission
regulation of centrosome duplication
protein transport
endosomal transport
viral life cycle
negative regulation of cytokinesis
multivesicular body assembly
viral budding via host ESCRT complex
regulation of viral process
ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway
regulation of mitotic spindle assembly
positive regulation of viral release from host cell
