Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
H00011261-M02
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
S2
抗原
CHP (AAH08373, 1 a.a. approximately 66 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MESHSVTQAG VQWRDLGSLQ PLPPGFKQFS HLSLPSSWDY RRVPPYLGNF CIFSGEGVSP CWPGWS
靶标信息
Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Involved in stress response. Prevents tumorigenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: calcineurin B homolog; Calcineurin B homologous protein 1; Calcineurin B-like protein; calcineurin homologous protein; calcineurin-like EF hand protein 1; calcineurin-like EF-hand protein 1; calcium binding protein P22; Calcium-binding protein CHP; Calcium-binding protein p22; EF-hand calcium-binding domain-containing protein p22; SLC9A1 binding protein
基因别名: CHP; CHP1; p22; p24; Sid470p; SLC9A1BP
UniProt ID: (Human) Q99653
Entrez Gene ID: (Human) 11261
microtubule bundle formation
negative regulation of protein phosphorylation
negative regulation of protein kinase activity
protein export from nucleus
potassium ion transport
small GTPase mediated signal transduction
negative regulation of phosphatase activity
calcium ion regulated exocytosis
membrane docking
hyaluronan catabolic process
cytoplasmic microtubule organization
negative regulation of protein ubiquitination
negative regulation of protein autophosphorylation
negative regulation of NF-kappaB transcription factor activity
positive regulation of sodium:proton antiporter activity
negative regulation of protein import into nucleus
protein stabilization
positive regulation of protein transport
protein oligomerization
regulation of intracellular pH
positive regulation of protein glycosylation
membrane organization
membrane fusion
negative regulation of calcineurin-NFAT signaling cascade
cellular response to acidic pH
positive regulation of protein targeting to membrane
regulation of neuron death
