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产品信息
MA5-38496
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
4A6B7
抗原
Purified recombinant fragment of human CHRM3 (aa: extra mix) expressed in E. Coli.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2898409
产品详细信息
This antibody has been tested in indirect ELISA.
靶标信息
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion of glandular tissue.
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生物信息学
蛋白别名: acetylcholine receptor; acetylcholine receptor, muscarinic 3; cholinergic receptor; cholinergic receptor, muscarinic 3; m3 muscarinic receptor; Muscarinic acetylcholine receptor M3
基因别名: CHRM3; EGBRS; HM3; PBS
UniProt ID: (Human) P20309
Entrez Gene ID: (Human) 1131
regulation of vascular smooth muscle contraction
cellular protein modification process
smooth muscle contraction
signal transduction
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway
phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
G-protein coupled acetylcholine receptor signaling pathway
synaptic transmission, cholinergic
nervous system development
cell proliferation
positive regulation of smooth muscle contraction
saliva secretion
