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产品信息
PA5-101398
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CHRNB1(Accession P11230), corresponding to amino acid residues L63-V113.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2850834
产品详细信息
Antibody detects endogenous levels of total CHRNB1.
靶标信息
The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: acetylcholine receptor; Acetylcholine receptor beta; Acetylcholine receptor subunit beta; acetylcholine receptor, nicotinic, beta 1 (muscle); AChR beta; cholinergic receptor; cholinergic receptor nicotinic beta polypeptide 1; cholinergic receptor, nicotinic beta 1; cholinergic receptor, nicotinic, beta 1 (muscle); cholinergic receptor, nicotinic, beta polypeptide 1 (muscle); Chrnb 1; nAChRB1
基因别名: Achr-2; ACHRB; Acrb; CHRNB; CHRNB1; CMS1D; CMS2A; CMS2C; RNACRB1; SCCMS
UniProt ID: (Human) P11230, (Rat) P25109, (Mouse) P09690
Entrez Gene ID: (Human) 1140, (Rat) 24261, (Mouse) 11443
postsynaptic membrane organization
skeletal muscle contraction
cation transport
muscle contraction
signal transduction
synaptic transmission, cholinergic
neuromuscular synaptic transmission
behavioral response to nicotine
regulation of membrane potential
muscle fiber development
neurological system process
cation transmembrane transport
ion transmembrane transport
transmembrane transport
transport
ion transport
