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Invitrogen
CHST11 Polyclonal Antibody
Product Details
PA5-103698
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human CHST11(Accession Q9NPF2), corresponding to amino acid residues A195-I245.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2853031
Product Specific Information
Antibody detects endogenous levels of total CHST11.
Target Information
Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues in desulfated dermatan sulfate. Preferentially sulfates in GlcA->GalNAc unit than in IdoA->GalNAc unit. Does not form 4, 6- di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: C4S-1; C4ST; C4ST-1; Carbohydrate sulfotransferase 11; chondroitin 4; Chondroitin 4-O-sulfotransferase 1; Chondroitin 4-sulfotransferase 1; IgH/CHST11 fusion
Gene Aliases: 1110020P09Rik; C4s; C4ST; C4ST-1; C4ST1; CHST11; HSA269537
UniProt ID: (Human) Q9NPF2, (Mouse) Q9JME2, (Rat) P69478
Entrez Gene ID: (Human) 50515, (Mouse) 58250, (Rat) 314694
chondrocyte development
respiratory gaseous exchange
post-embryonic development
carbohydrate biosynthetic process
chondroitin sulfate biosynthetic process
negative regulation of transforming growth factor beta receptor signaling pathway
polysaccharide localization
post-anal tail morphogenesis
regulation of cell proliferation
embryonic digit morphogenesis
negative regulation of apoptotic process
developmental growth
embryonic viscerocranium morphogenesis
carbohydrate metabolic process
chondroitin sulfate metabolic process
embryonic limb morphogenesis
embryonic skeletal system morphogenesis
cartilage development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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