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CHST14 Antibody (PA5-98690) in IHC (P)
Immunohistochemical analysis of CHST14 in paraffin embedded human pancreatic cancer using a CHST14 polyclonal antibody (Product # PA5-98690) at a dilution of 1:800. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is... View More
产品信息
PA5-98690
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human Carbohydrate sulfotransferase 14 protein (70-133AA)
偶联物
形式
Liquid
浓度
4.04 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% ProClin 300
保存条件
-20°C or -80°C if preferred
运输条件
Wet ice
RRID
AB_2813303
靶标信息
Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of dermatan sulfate. Plays a pivotal role in the formation of 4-0-sulfated IdoA blocks in dermatan sulfate. Transfers sulfate to the C-4 hydroxyl of beta1,4-linked GalNAc that is substituted with an alpha-linked iduronic acid (IdoUA) at the C-3 hydroxyl. Transfers sulfate more efficiently to GalNAc residues in -IdoUA-GalNAc-IdoUA- than in -GlcUA-GalNAc-GlcUA-sequences. Has preference for partially desulfated dermatan sulfate. Addition of sulfate to GalNAc may occur immediately after epimerization of GlcUA to IdoUA. GlcUA to IdoUA. Appears to have an important role in the formation of the cerbellar neural network during postnatal brain development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: carbohydrate (dermatan 4) sulfotransferase 14; carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14; Carbohydrate sulfotransferase 14; D4ST-1; dermatan 4 sulfotransferase 1; Dermatan 4-sulfotransferase 1; hD4ST1
基因别名: ATCS; CHST14; D4ST1; EDSMC1; HNK1ST; UNQ1925/PRO4400
UniProt ID: (Human) Q8NCH0
Entrez Gene ID: (Human) 113189
