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Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues of keratan. Mediates sulfation of keratan in cornea. Keratan sulfate plays a central role in maintaining corneal transparency. Acts on the non-reducing terminal GlcNAc of short and long carbohydrate substrates that have poly-N- acetyllactosamine structures.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: C-GlcNAc6ST; carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6; Carbohydrate sulfotransferase 6; corneal N-acetylglucosamine 6-sulfotransferase; Corneal N-acetylglucosamine-6-O-sulfotransferase; Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4-beta; GlcNAc6ST-5; gn6st-5; GST4-beta; hCGn6ST; N-acetylglucosamine 6-O-sulfotransferase 5
基因别名: CHST6; MCDC1
UniProt ID: (Human) Q9GZX3
Entrez Gene ID: (Human) 4166, (Dog) 489707