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CILP Antibody (PA5-47748) in WB
Western blot analysis of CILP in 0.2 mg/mL human cartilage tissue. Samples were incubated in CILP polyclonal antibody (Product # PA5-47748) using a dilution of 10 µg/mL followed by HRP-conjugated Anti-Goat IgG at a dilution of 1:50. A specific band was detected for CILP‚1 at approximately 133 kDa (as indicated). This experiment was conducted under reducing conditions and using the 66-440 kDa separation system..
产品信息
PA5-47748
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Mouse myeloma cell line NS0-derived recombinant human CILP-1 N-Terminal Fragment Arg22-Arg720
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2610074
产品详细信息
In direct ELISAs, less than 1% cross-reactivity with recombinant human CILP-1 C-terminal peptide is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein activity. The full-length and the N-terminal domain of this protein was shown to function as an IGF-1 antagonist. An allelic variant of this gene has been associated with lumbar disc disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cartilage intermediate layer protein 1; cartilage intermediate layer protein 1 C1; cartilage intermediate layer protein 1 C2; cartilage intermediate layer protein, nucleotide pyrophosphohydrolase; Cartilage intermediate-layer protein; CILP-1; HGNC:1980
基因别名: CILP; CILP-1; HsT18872; UNQ602/PRO1188
UniProt ID: (Human) O75339
Entrez Gene ID: (Human) 8483
