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CNSK1A1 (CK1 alpha 1) is a member of the casein kinase I (CKI) gene family, which encodes serine/threonine kinases that preferentially phosphorylate acidic substrates. CKI proteins are monomeric, ranging from 25 to 55 kD, and are found in the nuclei, cytoplasm, and membrane fractions of eukaryotic cells. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Casein kinase I isoform alpha; CK I alpha; CK-I alpha; CK1; CKI alpha; CKI-alpha; CSNK1A1/CK1; OTTHUMP00000224000; OTTHUMP00000224001; OTTHUMP00000224003; YIL035C
基因别名: Csnk1a1
UniProt ID: (Rat) P97633
Entrez Gene ID: (Rat) 113927