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产品信息
PA5-53036
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human CLCC1. Recombinant protein control fragment (Product #RP-90165).
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2639852
产品详细信息
Immunogen sequence: HDDDWIDPTD MLNYDAASGT MRKSQAKYGI SGEKDVSPDL SCADEISECY HKLDSLTYKI DECEKKKRED YESQSNPVFR RYLNKILIEA GKLGLL
Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 81%.
靶标信息
Neurofibromin is a member of the GTPase-activating (GAP) class of proteins. These proteins enhance the GTPase activity of signaling G-Proteins like Ras. The NF1 gene is also classified as a tumor suppressor gene, and many studies have shown that mutations at the NF1 locus produce neurofibromas, rhabdomyosarcomas, leimyosarcomas, mental retardation and memory deficiency. Neurofibromin has also been associated with the intermediated filaments of the cytoskeleton. NF1 is expressed at its highest levels during periods of desmosome formation and mutations of NF1 produce variable cell sizes and morphologies.
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生物信息学
蛋白别名: chloride channel CLIC-like 1; Chloride channel CLIC-like protein 1; ER anion channel 1; ERAC1; Mid-1-related chloride channel protein; Mid-1-related chloride channel protein 1
基因别名: CLCC1; KIAA0761; MCLC
UniProt ID: (Human) Q96S66
Entrez Gene ID: (Human) 23155
