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产品信息
PA5-121065
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-253 of human CLIC4 (NP_039234.1).
偶联物
形式
Liquid
浓度
0.66 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2914637
产品详细信息
Positive test controls include: SW620, Mouse kidney, Rat brain, Rat kidney. The target is usually found in the following locations: Cell junction, Cell membrane, Cytoplasm, Cytoplasmic vesicle membrane, Mitochondrion, Nucleus matrix, Single-pass membrane protein, centrosome, cytoskeleton, microtubule organizing center.
Immunogen sequence: MALSMPLNGL KEEDKEPLIE LFVKAGSDGE SIGNCPFSQR LFMILWLKGV VFSVTTVDLK RKPADLQNLA PGTHPPFITF NSEVKTDVNK IEEFLEEVLC PPKYLKLSPK HPESNTAGMD IFAKFSAYIK NSRPEANEAL ERGLLKTLQK LDEYLNSPLP DEIDENSMED IKFSTRKFLD GNEMTLADCN LLPKLHIVKV VAKKYRNFDI PKEMTGIWRY LTNAYSRDEF TNTCPSDKEV EIAYSDVAKR LTK
靶标信息
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 4 (CLIC4) protein, encoded by the CLIC4 gene, is a member of the p64 family; the gene is expressed in many tissues and exhibits a intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells).
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生物信息学
蛋白别名: chloride intracellular channel 4 (mitochondrial); chloride intracellular channel 4 like; Chloride intracellular channel protein 4; DKFZP566G223; FLJ38640; Glutaredoxin-like oxidoreductase CLIC4; Intracellular chloride ion channel protein p64H1; mc3s5/mtCLIC; mitochondrial chloride intracellular channel 4
基因别名: CLIC4; CLIC4L; D0Jmb3; H1; huH1; mc3s5; MTCLIC; p64H1; TU-74
UniProt ID: (Human) Q9Y696, (Mouse) Q9QYB1, (Rat) Q9Z0W7
Entrez Gene ID: (Human) 25932, (Mouse) 29876, (Rat) 83718
angiogenesis
endothelial cell morphogenesis
glutathione metabolic process
chloride transport
apoptotic process
vacuolar acidification
fertilization
cell differentiation
keratinocyte differentiation
negative regulation of cell migration
regulation of ion transmembrane transport
establishment or maintenance of apical/basal cell polarity
multicellular organism growth
branching morphogenesis of an epithelial tube
regulation of cytoskeleton organization
retina vasculature morphogenesis in camera-type eye
cellular response to calcium ion
chloride transmembrane transport
transport
ion transport
