Invitrogen

CLIC4 Polyclonal Antibody

CLIC4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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CLIC4 Antibody (PA5-82328) in IHC (P)

Immunohistochemical analysis of CLIC4 in human kidney using CLIC4 Polyclonal Antibody (Product # PA5-82328) shows strong membranous and cytoplasmic positivity in cells in tubules.

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CLIC4 Antibody — Relative expression in western blot: Antibody specificity was demonstrated by detection of known differential basal expression of the target across tissue/cell models. Expression of CLIC4 was observed specifically in SK-MEL-30 cells and in MCF-7 cells using anti-CLIC4 Polyclonal Antibody (Product #PA5-82328) in western blot. The relative expression levels of CLIC4 within each cell line is shown using RNA-Seq. {RE}

产品信息

PA5-82328

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.04-0.4 µg/mL

免疫组化（石蜡） (IHC (P))

1:500-1:1,000

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human CLIC4. Recombinant protein control fragment (Product #RP-89617).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.05 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2789487

产品详细信息

Immunogen sequence: THPPFITFNS EVKTDVNKIE EFLEEVLCPP KYLKLSPKHP ESNTAGMDIF AKFSAYIKNS RPEANEALER GLLKTLQKLD EYLNSPLPDE IDENSMEDIK FSTRKFLDGN EMTLADCNLL PKLHIVKVVA KKYRNFDIPK EMTGI

靶标信息

Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 4 (CLIC4) protein, encoded by the CLIC4 gene, is a member of the p64 family; the gene is expressed in many tissues and exhibits a intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells).

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: chloride intracellular channel 4 like; Chloride intracellular channel protein 4; DKFZP566G223; FLJ38640; Glutaredoxin-like oxidoreductase CLIC4; Intracellular chloride ion channel protein p64H1

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基因别名: CLIC4; CLIC4L; H1; huH1; MTCLIC; p64H1

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UniProt ID: (Human) Q9Y696

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Entrez Gene ID: (Human) 25932

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功能

glutathione transferase activity voltage-gated ion channel activity chloride channel activity protein binding ion channel

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